University of Bristol Other PhD Projects, Programmes & Scholarships

We have 35 University of Bristol Other PhD Projects, Programmes & Scholarships

Integrative genomics prioritisation of drug targets

University of Bristol Bristol Medical School

The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more

Supervisor: Prof T Gaunt

20 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Self-funded PhD- Understanding the molecular mechanism of a bacterial genome defence system and its synergy with CRISPR-Cas

University of Bristol School of Biochemistry

Prokaryotes have evolved over billions of years alongside their viruses, the bacteriophages, or “phages”. To prevent viral infection, prokaryotes have evolved rudimentary immune mechanisms, the most widespread and well-studied of which are the Restriction-Modification and the CRISPR-Cas enzymes. Read more

Supervisor: Prof M D Szczelkun

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding the role of adiponectin in kidney disease development at a population level

University of Bristol Bristol Medical School

Reduced circulating adiponectin levels are associated with poor outcome in patients with diabetic kidney disease (DKD) (1). Adiponectin has been shown to be protective against the development of DKD in Type 2 diabetic models (2, 3, 4). Read more

Supervisor: Dr R Foster

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the interactions of incretin hormone mimetics with hypothalamo-neurohypophysial system arginine vasopressin and oxytocin release

University of Bristol Bristol Medical School

Our research focus over decades has been the osmoregulatory function of a special collection of neurones in a part of the brain called the hypothalamus. Read more

Supervisor: Prof D Murphy

Year round applications PhD Research Project Self-Funded PhD Students Only

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Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

University of Bristol Bristol Medical School

Genome wide association studies (GWAS) have discovered many genetic associations for traits and diseases. However, most GWAS signals reside in non-coding regions (outside genes), and it is likely that GWAS variants confer their effects through modulating regulatory mechanism. Read more

Supervisor: Dr J Min

Year round applications PhD Research Project Self-Funded PhD Students Only

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Endothelial glycocalyx damage as a therapeutic target in sepsis-associated Acute Kidney Injury

University of Bristol Bristol Medical School

Sepsis is the leading cause of acute kidney injury (sAKI), associated with high morbidity and mortality.1,2 Unfortunately, there is no treatment for sAKI, current therapies are nonspecific and supportive of the vital organ systems in the hope the kidney will recover. Read more

Supervisor: Prof S Satchell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Creating patient-specific retinal organoids from human induced pluripotent stem cells for in vitro simulation of uveitis

University of Bristol Bristol Medical School

Uveitis, although uncommon, is a notable cause of visual impairment and blindness. Uveitis encompasses a range of conditions driven by both innate autoinflammatory and adaptive autoimmune CD4 T-cell responses. Read more

Supervisor: Dr P Maghsoudlou

Year round applications PhD Research Project Self-Funded PhD Students Only

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What outcomes are important to patients with osteoarthritis? Development of a core outcome set

University of Bristol Bristol Medical School

Osteoarthritis is the most common musculoskeletal condition worldwide and is the leading cause of disability in the UK. In our recent study to identify research priorities in osteoarthritis, the highest priority question to patients was “What outcomes are important to patients?”[1]. Read more

Supervisor: Prof M Whitehouse

Year round applications PhD Research Project Self-Funded PhD Students Only

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Epilepsy and the ageing brain

University of Bristol Bristol Medical School

Our ability to remember ‘where I put my car keys today’ instead of ‘where I put them yesterday’ depends on a computational process called pattern separation. Read more

Supervisor: Dr D Atan

Year round applications PhD Research Project Self-Funded PhD Students Only

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4-year PhD Studentship: Towards Accurate Disease Surveillance: Deep Learning-Assisted Simulation of Bacterial Genomes

University of Bristol Bristol Veterinary School

Public health surveillance programmes routinely collect vast amounts of pathogen genomics data each year. A pressing issue is how to best utilise this information for effective disease monitoring and management. Read more

Supervisor: Prof K Reyher

Year round applications PhD Research Project Self-Funded PhD Students Only

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4-year PhD Studentship: Impact of the microbial biodiversity and micro-ecological processes on the transmission and persistency of diseases in dairy farms: a multidisciplinary, adaptive research approach

University of Bristol Bristol Veterinary School

Soil provides the basic structure for the development of the ecosystem where humans and animals live. Soil microbiota, including different pathogenic and non-pathogenic microorganisms, are responsible for the health and maintenance of the ecosystem, creating the greatest biodiversity in the world. Read more

Supervisor: Dr B Amato

Year round applications PhD Research Project Self-Funded PhD Students Only

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4-year PhD Studentship: Combatting bacterial zoonoses through multi-disciplinary studies of virulence factors

University of Bristol Bristol Veterinary School

Vector-borne diseases, including bacterial zoonoses, pose a significant threat to human and animal health and to livestock industries, particularly in low and middle-income countries. Read more

Supervisor: Dr T Cogan

Year round applications PhD Research Project Self-Funded PhD Students Only

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The genetic map of human molecular phenotypes

University of Bristol Bristol Medical School

Rationale. Genome wide associations studies (GWASs) have discovered many genetic associations with a large range of human traits, but the functional consequences of GWAS signals often remain elusive, as most GWAS signals reside in non-coding genomic regions. Read more

Supervisors: Dr J Min, Dr G Hemani, Dr JH Hawe

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Estimating the global cancer burden due to low levels of physical activity

University of Bristol Bristol Medical School

Rationale. Around 40% of all cancers are thought to be avoidable by modification of lifestyle factors. Obesity has been found to be a risk factor for several cancers and was estimated to have caused around 3.6% of all new cancers which occurred in 2012. Read more

Supervisors: Dr S Lewis, Prof R Martin, Dr R Pulsford, Prof R Jago, Dr FB Bray

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Prospectively mapping the development of liver disease amongst young adults. Who is developing it early and why?

University of Bristol Bristol Medical School

Rationale. Historically, cirrhosis (irreversible liver scarring), often due to alcohol-related liver disease (ARLD) and non-alcoholic fatty liver disease (NAFLD), presents in the 5th and 6th decade. Read more

Supervisors: Dr KA Abeysekera, Prof M Hickman, Prof N Timpson

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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We have 35 University of Bristol Other PhD Projects, Programmes & Scholarships

University of Bristol Other PhD Projects, Programmes & Scholarships

We have 35 University of Bristol Other PhD Projects, Programmes & Scholarships

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