The Newcastle-Liverpool-Durham DTP is a strategic Partnership in Biosciences doctoral training between three research-intensive universities in northern cities of great industrial heritage, Newcastle University, the University of Liverpool and Durham University.
The Partnership is offering up to 22 four-year BBSRC-funded studentships starting in October 2017. A wide range of projects across the Partnership are available for application under the broad themes of Agriculture & Food Security, Bioscience for Health and World Class Bioscience:
|Bacterial folate synthesis and long-term health||Details|
|Copper-handling by Polaris and the metallation-status of ETR1||Details|
|Regulation of root growth under osmotic stress conditions: a systems study||Details|
|The evolution of inbreeding depression in wild flax, and implications for crop development||Details|
|The role of chaperone networks in skin ageing||Details|
|The structure-function studies of small heat shock proteins; linking the stress response to successful ageing||Details|
|Unraveling the role of pyrabactin resistance proteins in plant stress responses and plant development||Details|
|Using biochemical and evolutionary approaches to characterize novel enzymes as possible drug targets in apicomplexan parasites of economically important livestock||Details|
|Developing and exploiting a molecular understanding of multiple herbicide resistance in grass weeds||Details|
|Computational modeling of type I collagen synthesis: development of an in silico system to investigate age-related tissue degeneration and fibrosis.||Details|
|Determination of laminin LN domain roles in tissue function, using Pierson syndrome and the lens capsule as a model.||Details|
|Towards preventing digital dermatitis transmission between dairy cows.||Details|
|A new approach for effective field monitoring of pest species||Details|
|CDK18-dependent regulation of the DNA damage response||Details|
|Engineering more water-use efficient crops: functional genomics of weak and strong Crassulacean acid metabolism in diverse species of the genus Kalanchoë||Details|
|Evolutionary insights for engineering improved globin oxygen carriers||Details|
|How does the autism-related protein Shank contribute to the regulation of neuronal spine plasticity?||Details|
|Quantifying the role of phosphohistidine during bacterial infection||Details|
|Repurposing cyanobacterial CO2-fixing organelles using synthetic biology||Details|
|Understanding effects of sulfation of physical and chemical characteristics of polysaccharides: new renewable biopolymers for personal care products.||Details|
|Stem cell pluripotency: Impact of bio-inspired substrates on integrin-dependent signalling and force transmission||Details|
|Chromatin Control of Autophagy||Details|
|Elucidating new redox-signalling mechanisms mediating responses to reactive oxygen species (ROS)||Details|
|Investigating the impact of Mitochondrial Reverse Electron Transport on cellular and organism ageing.||Details|
|Investigating the role of a cytosolic copper storage protein in Pseudomonas aeruginosa and the link to pathogenicity||Details|
|Investigating the role of mitochondria in stem cell biology||Details|
|mTOR signalling: mechanisms of regulation in young and senescent cells||Details|
|Probing the physical mechanisms of Bacillus subtilis cell division in living cells, one molecule at a time||Details|
|Rapid throughput CRIPSR/Cas9 based mutagenesis to analyse the functional importance of NF-kB subunit post-translational modifications||Details|
|Regulation of transcription elongation||Details|
|Structure and Function of DNA topoisomerase IIB||Details|
|The molecular structure and function of the synaptonemal complex in chromosome synapsis and recombination during meiosis||Details|
|Understanding the dynamic interactions between Salmonella and the intestinal microbiota||Details|
|Why is the bacterial mRNA degradation machinery membrane associated?||Details|
|Effects of inflammatory disease on development of preimplantation embryos in cattle||Details|
|Understanding herbicide selectivity using a pharmacokinetic approach||Details|
|Engineering synthetic metabolic compartments in bacteria||Details|
|Quantifying and Engineering Asymptomatic Viruses in Grasses||Details|
BBSRC DTP iCASE awards enable students to undertake research projects that involve both an academic and non-academic partner. iCASE studentships provide outstanding students with access to training, facilities and expertise not available in an academic setting. The partner organisation also benefits from recruiting a motivated, doctoral student who is capable of undertaking cutting-edge research.
All studentships will cover a tax-free stipend at the Research Council UK rate (indicative amount in year 1 in 2016-17, £14,296), research costs and tuition fees, and are available to UK students and to EU citizens who have been in the UK for the three years prior to the academic year 2017-18. Fees only studentships (no stipend) are available to EU citizens who have been a resident of the EU but not UK.
Further information about eligibility for Research Council UK funding can be found here .
Students who have, or are expecting to attain at least an upper second class honours degree (or equivalent) in relevant biological subjects, are invited to apply by email and CV to the project supervisor by 5 January 2017.
The multidisciplinary training experience and interdisciplinary nature of some of the projects means that we welcome applications from students with physical science and mathematical backgrounds who are interested in using their skills to address the challenges of 21st century bioscience research.