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MRC & Asthma UK Centre in Allergic Mechanisms of Asthma

PhD Studentship in Allergic Mechanisms of Asthma

The MRC-Asthma UK Centre in Allergic Mechanisms of Asthma is a partnership between the Medical Research Council, Asthma UK, Imperial College London, King’s College London and partner NHS Trusts to advance our understanding of the pathogenesis of asthma. The Centre provides an outstanding opportunity for high-calibre PhD students to train in areas of basic and clinical science that have direct relevance to the development of novel approaches for the prevention and treatment of asthma.

Applications are now invited for a 3-yr PhD studentship to commence in January 2018. The successful candidate will be able to choose from a broad range of PhD projects based at Imperial College London covering the various interests of the Centre. Examples of some of the projects offered are listed below:

  • Chemokine Biology in Asthma Pathogenesis – Dr. James Pease
  • Development of pulmonary immunity in early life – Prof. Clare Lloyd
  • Epithelial-macrophage interactions driving pulmonary inflammation - Prof. Clare Lloyd
  • Functional dissection of GSDMB domains and its potential roles in airway inflammation – Dr. Youming Zhang
  • Identification of proteins that regulate ORMDL3 in epithelial inflammation – Dr. Youming Zhang
  • Mechanisms mediating viral induced wheezing and factors determining progression to severe childhood asthma – Prof. Sejal Saglani
  • Mitochondrial oxidative and nitrative stress in eosinophilic asthma – Prof. Fan Chung
  • Statistical causal modelling approach to understanding the developmental profiles of asthma and allergy – Prof. Adnan Custovic
  • The role of macrophage metabolic reprogramming in asthma – Dr Adam Byrne
  • The interplay between innate and adaptive immunity in the inception of asthma in early life – Prof. Sejal Saglani
  • Understanding treatable traits using the U-BIOPRED cohort – Prof. Ian Adcock

Imperial College London provides excellent opportunities for research students' training. All students benefit from a full programme of training in research and transferable skills organised through the Graduate School, the quality of which has been recognised several times at the Times Higher Education (THE) Awards.

The advertised studentship is predominantly restricted to home or EU candidates based on the nature of the funding. Students from outside the EU area would be required to pay substantially higher tuition fees that would not be covered by these studentship awards.

How to Apply

Applicants must be in receipt of, or due to receive Master UK Degree or equivalent in an appropriate subject (Merit and above).

To apply, send your CV, names of two referees and a one page personal statement to Jana Pierron at [email protected]

Closing date for the full application is Sunday 5th November 2017. All successful applicants will be contacted in mid-November and invited for interviews on 20th November 2017. Please assume that your application has not been successful if you have not heard from us within a month of the closing date.

Please note that all candidates must fulfil College admissions criteria.

Committed to equality and valuing diversity. We are an Athena SWAN Silver Award winner, a Stonewall Diversity Champion, a Two Ticks Employer, and are working in partnership with GIRES to promote respect for trans people.


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