4 Year PhD Studentship 2017
RNA and Computational Biology Group

“Applying High Performance Computing to the Cancer Genome”

The RNA Biology Group is interested in the processes that regulate gene expression, and how these are altered in cancer. A major focus of the group is on the role of noncoding RNAs in modulating gene expression. We are offering a 4-year PhD studentship to develop new computational approaches to study these systems. Focusing on epigenetics, the project will integrate data generated from a variety of state of the art techniques including DNA and RNA sequencing, ChIP- and ChIRP-seq, and will work with a mixture of in house and public domain datasets.

The successful applicant will join a highly interdisciplinary research group that combines computational biology, bench and clinical science. They will have access to a large High Performance Computing system, with ~2,000 cores and 33TB RAM, and will collaborate closely with bench scientists within the group, to confirm hypotheses generated through in silico analyses.

While a background in biology is useful, the project is computational in nature, and excellent scientists from a computational background who are keen to develop a better understanding of cancer, are also encouraged to apply.

Informal enquiries should be addressed to Dr Crispin Miller

Closing Date: Thursday 13 April 2017 (2400 hrs)
Interview Date: Friday 28 April 2017

Interested students will find full project descriptions, entry criteria and application form at the CRUK Manchester Institute website