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  PhD Studentship in the School of Computing - Computational Biology - Computational Modelling of Cryopreservation of Biological Tissue


   School of Computing

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  Dr R Bauer  No more applications being accepted  Funded PhD Project (Students Worldwide)

About the Project

Number of awards

1

Start date and duration

Ideally November 2018 for three years.

Application closing date

30 September 2018.

Overview

Interested in computers as well as biology? Then this project might be what you are looking for! The aim is to use novel software and high-performance computers to model how biological tissue behaves during freezing and thawing.

Cryopreservation of biological tissue is in its infancy. State-of-the-art freezing and thawing techniques lead to tissue damage in anything larger than 1-3 mm3. Above-freezing storage times of human organs range from approximately 3 to 24 hours - depending on organ - before becoming unviable. This lack of preservation capacity results in 2/3 of donor hearts and 4/5 of lungs being rejected for transplant for logistical reasons.

By improving our knowledge of how cryogenic processing affects biological tissue, new methodologies for cryogenic processing will be studied. To this end, you will work together with experts in the field, learn to incorporate the results in detailed 3D computer simulations, and produce novel hypotheses that will generate better methodologies.

This project will enable you to gain highly interdisciplinary skills. You will be supervised by a multidisciplinary team comprising computational biologists and experimental researchers. You will be based at Newcastle University, and also collaborate with computer scientists at CERN to learn the usage and extension of a novel software platform called BioDynaMo (https://biodynamo.web.cern.ch). Moreover, you will participate at weekly lab meetings of the supervisory team, and present your findings at international conferences and scientific journals.

Sponsor

School of Computing (https://bit.ly/2Prmj0o)

Name of supervisor(s):

Dr Roman Bauer (https://bit.ly/2Mqmlb6) (School of Computing), Professor Marcus Kaiser (School of Computing).

Eligibility Criteria:

You must have, or expect to achieve, at least a 2:1 honours degree or international equivalent, in physics, computer science, engineering, mathematics or a related subject.

How to apply

You must apply through the University’s online postgraduate application system. To do this please choose ‘Apply now’ (https://bit.ly/2PslTaj).

All relevant fields should be completed, but fields marked with a red asterisk must to be completed. The following information will help us to process your application. You will need to:
•insert the programme code 8050F in the programme of study section
•select ‘PhD Computer Science (Full Time) Bioinformatics (Computing)’ as the programme of study
•insert the studentship code COMP009 in the studentship/partnership reference field
•attach a covering letter and CV. The covering letter must state the title of the studentship, quote reference code COMP009 and state how your interests and experience relate to the project
•attach degree transcripts and certificates and, if English is not your first language, a copy of your English language qualifications.

You should also send your covering letter and CV by email to [Email Address Removed].

Funding Notes

100% of UK/EU tuition fees paid and annual living expenses of £14,777 (full award). Successful international candidates will be required to make up the difference between the UK/EU fees and international fees. Also significant additional funding to cover research costs and local, national and international travel (conferences and exchanges).