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The pharmacological relevance of pro-peptide of GDNF family members

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  • Full or part time
    Dr Marko Hyvonen
  • Application Deadline
    No more applications being accepted
  • Funded PhD Project (European/UK Students Only)
    Funded PhD Project (European/UK Students Only)

Project Description

Applications are invited for a PhD position, starting in October 2016, in a BBSRC-funded collaborative project between Dr Marko Hyvonen at University of Cambridge (http://www.bioc.cam.ac.uk/people/uto/hyvonen)
and Dr Lutz Jermutus at MedImmune (http://www.medimmune.com) to study precursor forms of growth factors from TGFbeta family using biochemical, biophysical structural and pharmacological methods. The project will be done mostly in the group of Marko Hyvonen at the Department of Biochemistry (http://www.bioc.cam.ac.uk) with up to 18 months to be spent at MedImmune research laboratories in Cambridge.

The student will learn molecular biology, protein biochemistry, biophysics and structural biology in the academic lab. At MedImmune they will learn cell-based assays and techniques for pharmacological evaluation of the target protein’s properties. The student will be trained in state-of-the-art technologies and benefit from being enbedded in two lead laborotories, thus gain invaluvable insight from cross-disciplinary research in academia and in industry, preparing them for future career in either environment.

The candidate should have a first or upper second (II.i) class degree in biochemistry or closely related subject and prior experience in molecular and cellular biology and in protein biochemistry. Experience in protein expression and purification, biophysical measurement of interactions and in protein crystallography would advantageous.

Applications should be sent Dr Marko Hyvonen (mh256@cam.ac.uk) as a single PDF file containing a CV of no longer than three pages (including details of final grade or expected grade) and a motivational statement of up to two pages. Applicants should include also contact details of at least two academic referees. There is no need to send transcripts of degree certificates.

Deadline for applications is February 5th and shortlisted candidates will be interviewed soon after that.

Informal enquiries can be addressed by email to Dr Hyvonen (mh256@cam.ac.uk).

Funding Notes

BBSRC iCASE studentships are available to UK nationals and EU students who meet the UK residency requirements. Further information about eligibility for Research Council UK funding can be found on the BBSRC website:

How good is research at University of Cambridge in Biological Sciences?

FTE Category A staff submitted: 189.63

Research output data provided by the Research Excellence Framework (REF)

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