Pathogenicity and Colonisation by Staphylococcus aureus and Streptococci
The research carried out in my laboratory is aimed at understanding how important human pathogens such as Staphylococcus aureus, Streptococcus agalactiae and Streptococcus pyogenes, are able to colonise the human host, resist its defences and cause disease. I am particularly interested in the effect that surface structures have on these processes. I have a number of projects, including collaboration with colleagues, in the following areas:
i. Gut microbial ecology with colleagues in the School of Food Biosciences. We are currently investigating the ability of S. aureus to colonise and persist within the human gut.
ii. We are investigating the modulation of platelet signalling by Gram positive pathogens.
iii. The effects of metal ion homeostasis on the physiology of Gram positive pathogens.