Applicants should already have or be expected to obtain a First or upper Second Class degree in a relevant discipline. This studentship is fully funded for three years. It covers tuition fees at the UK/EU rate and includes a stipend at the standard Research Council rate (currently £16,296 per annum). Funding is available for UK and EU students.
Otto, Sharma and Williams (2016) Non-Catalytic Roles of Presenilin throughout evolution. Journal of Alzheimer’s disease, 52(4):1177-87.
Otto et al and Williams (2016) Employing Dictyostelium as an advantageous 3Rs model for pharmacogenetic research. In Methods in Molecular Biology: Chemotaxis,1407,123-130.
Chang et al and Williams (2016) Seizure control by decanoic acid through direct AMPA receptor inhibition. Brain, 139(Pt 2):431-43.
Cocorocchio et al and Williams (2016) Bitter tastant responses in the amoeba Dictyostelium correlate with rat and human taste assays. ALTEX, 33(3):225-36.
Walker and Williams (2016) Identifying the molecular mechanism of the MCT (ketogenic) diet. In ‘Ketogenic Diet and Metabolic Therapies: Expanded Roles in Health and Disease’, Oxford University Press edited by Susan Masino. ISBN: 9780190497996
Zuckermann, La Ragione, Baines, and Williams (2015) Valproic acid protects against haemorrhagic shock-induced signalling changes via PPARγ activation in an in vitro model. British Journal of Pharmacology, 172(22):5306-17.
Chang et al and Williams (2014) Seizure control by derivatives of medium chain fatty acids associated with the ketogenic diet show novel branching-point structure for enhanced potency. Journal of Pharmacology and Experimental Therapeutics, 352(1):43-52.
Ludtmann et al and Williams (2014) An ancestral non-proteolytic role for presenilin proteins in multicellular development of the social amoeba Dictyostelium discoideum. Journal Cell Science. 127(7):1576-84.
Cunliffe et al and Williams (2014) Epilepsy Research Methods Update: Understanding the causes of epileptic seizures and identifying new treatments using non-mammalian model organisms Seizure, 24,44-51
Waheed et al, Williams* and Carew* (2013) Naringenin inhibits the growth of Dictyostelium and MDCK-derived cysts in a polycystin-2 (TRPP2)-dependent manner. British Journal Pharmacology.171(10):2659-70.
Robery et al and Williams (2013) A novel human receptor involved in bitter tastant detection identified using the model organism Dictyostelium discoideum. Journal of Cell Science, 126(23):5465-76
Chang, Walker and Williams (2013) Seizure-induced reduction in PIP3 levels contributes to seizure-activity and is rescued by valproic acid. Neurobiology of Disease. 62C:296-306
Chang et al and Williams (2013) Seizure control by ketogenic diet-associated medium chain fatty acids. Neuropharmacology, 69:105-14
Chang et al and Williams (2012) The anti-epileptic valproic acid and other medium chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium. Disease Models and Mechanism,5,115-124.
FTE Category A staff submitted: 24.00
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