• University of Bristol Featured PhD Programmes
  • University of Leeds Featured PhD Programmes
  • London School of Economics and Political Science Featured PhD Programmes
  • Carlos III Health Institute Featured PhD Programmes
  • University of Cambridge Featured PhD Programmes
  • University of Mannheim Featured PhD Programmes
  • University of Glasgow Featured PhD Programmes
  • University of Leeds Featured PhD Programmes
Wellcome Trust Featured PhD Programmes
University College London Featured PhD Programmes
University of Kent Featured PhD Programmes
Newcastle University Featured PhD Programmes
University of Reading Featured PhD Programmes

Uncovering genetic mechanisms of cancer-associated cell phenotypes to identify potential new therapeutic targets

  • Full or part time
  • Application Deadline
    Applications accepted all year round
  • Self-Funded PhD Students Only
    Self-Funded PhD Students Only

About This PhD Project

Project Description

Cancer cells can continually acquire new phenotypes such as therapeutic resistance that drive disease progression and lead to poor prognosis. How cells initiate and evolve resistance to many commonly used therapeutic agents is poorly understood, preventing the development of new more effective therapeutic strategies. The goal of this Ph.D. project is to develop novel approaches in both budding yeast and human cell culture model systems to uncover how cancer-associated cell phenotypes such as therapeutic resistance are controlled at the genetic level, ultimately to understand their molecular mechanisms and identify potential new therapeutic targets. This project offers an excellent opportunity to work with two different model systems, acquire bioinformatics skills, and develop and use state-of-the-art techniques in quantitative genetics, genomics, CRISPR/Cas9 genome editing and molecular biology. This project will make significant advances in our understanding of how cancer-associated cell phenotypes develop, and will ultimately shed light on how cancers arise and evolve.

Email Now

Insert previous message below for editing? 
You haven’t included a message. Providing a specific message means universities will take your enquiry more seriously and helps them provide the information you need.
Why not add a message here
* required field
Send a copy to me for my own records.
Email Sent

Share this page:

Cookie Policy    X