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Integrated Approaches to the Molecular Microbiology of Bacterial Pathogens

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  • Full or part time
    Prof Maiden
  • Application Deadline
    Applications accepted all year round
  • Competition Funded PhD Project (Students Worldwide)
    Competition Funded PhD Project (Students Worldwide)

Project Description

Bacteria have been on the planet for 3.5 billion years and are found in all environments. Bacterial pathogens of animals and humans have evolved on multiple occasions from this ancient and diverse population. We adopt a highly collaborative, explicitly evolutionary and ecological approach to understanding bacterial diseases which aims to unify genomic studies with functional investigations of disease-associated phenotypes. Specific areas of research include meningococcal disease, campylobacteriosis, and bioinformatics. We have particular interests in translational public health interventions including vaccination and source attribution.

Web: http://maidenlab.zoo.ox.ac.uk



Funding Notes

Funding is competitive, via either University/Departmental Studentships or Doctoral Training Centres (http://www.zoo.ox.ac.uk/graduates/applying). Also see: http://www.ox.ac.uk/admissions/graduate/courses/dphil-infection-immunology-and-translational-medicine

References

Some recent references:

1. Daugla, D., Gami, J., Gamougam, K. et al. (2013). Effect of a serogroup A meningococcal conjugate vaccine (PsA-TT) on serogroup A meningococcal meningitis and carriage in Chad: a community trial. Lancet 383, 40-47.

2. Griekspoor, P., Colles, F. M., McCarthy, N. D., Hansbro, P. M., Ashhurst-Smith, C., Olsen, B., Hasselquist, D., Maiden, M. C. & Waldenstrom, J. (2013). Marked host specificity and lack of phylogeographic population structure of Campylobacter jejuni in wild birds. Mol Ecol 22, 1463-1472.

3. Maiden, M. C., van Rensburg, M. J., Bray, J. E., Earle, S. G., Ford, S. A., Jolley, K. A. & McCarthy, N. D. (2013). MLST revisited: the gene-by-gene approach to bacterial genomics. Nature Reviews Microbiology 11, 728-736.

How good is research at University of Oxford in Biological Sciences?

FTE Category A staff submitted: 223.80

Research output data provided by the Research Excellence Framework (REF)

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