• London School of Economics and Political Science Featured PhD Programmes
  • University of Bristol Featured PhD Programmes
  • Carlos III Health Institute Featured PhD Programmes
  • University of Cambridge Featured PhD Programmes
  • University of Leeds Featured PhD Programmes
  • University of Glasgow Featured PhD Programmes
  • University of Mannheim Featured PhD Programmes
  • University of Leeds Featured PhD Programmes
Wellcome Trust Featured PhD Programmes
University College London Featured PhD Programmes
Imperial College London Featured PhD Programmes
University of Warwick Featured PhD Programmes
University of Bristol Featured PhD Programmes

Tissue imaging improving spatially resolved metabolomic analysis of tissue sections characterization.

This project is no longer listed in the FindAPhD
database and may not be available.

Click here to search the FindAPhD database
for PhD studentship opportunities
  • Full or part time
    Prof Takats
    Dr Goodwin
  • Application Deadline
    Applications accepted all year round
  • Funded PhD Project (European/UK Students Only)
    Funded PhD Project (European/UK Students Only)

About This PhD Project

Project Description

The research will use mass spectrometry imaging technologies to characterise tissues sections. The focus will be on metabolomic and lipidomic analysis of a number of tissues with the aim of identifying and differentiating specific metabolomic profiles within the tissues. The student will optimize, validate and employ DESI imaging analysis on a range of samples and develop quantitation strategies, evaluate sample preparation and processing protocols. They will also undertake to improve the spatial resolution and speed of analysis. As well as data collection, the project will aim to evaluate and develop improved database interrogation systems for better understanding metabolomic imaging data. The student will liaise with AstraZeneca experts to enable integration of imaging data with their workflows.

Prof. Zoltán Takáts and his group are world leaders in ambient ionization analysis of clinical and pre-clinical tissues. He has personally developed DESI as well as numerous other ionization techniques. His group and collaborators have been developing tools for the analysis of metabolomic datasets collected from wide ranging samples and analytical assays. AstraZeneca are at the forefront of pharmaceutical companies applying mass spectrometry imaging to drug discovery and development.
Share this page:

Cookie Policy    X