The Ferrier Research Institute, Victoria University of Wellington
Natural products have provided the inspiration for a number of drugs currently used to treat a wide range of ailments. One of the most well-known and widely used examples is aspirin, originally extracted from willow bark in the form of a glycoside. To ensure optimum efficacy with minimum side effects, synthesis chemists produce analogues of the lead compound, which are subjected to appropriate biological and toxicity assays.
This PhD project will use selected natural products as substrates for advanced chemical manipulations that will lead to structurally diverse materials in multi-step syntheses. This will require good synthetic skills and will expose the successful candidate to a range of different chemical transformations, including stoichiometric chemistry and catalysed processes. There will be the opportunity for the successful candidate to work alongside colleagues in the Biological Sciences to perform some of these assays in person.
Dr Bradley Williams and Dr Simon Hinkley have extensive experience working with and modifying natural product substrates towards the production of biologically active molecules.
Full stipend of NZ$23,500 plus a contribution to fees of up to NZ$8,000 per annum for 3 years.
Interested candidates are encouraged to contact Rachael Odlin ([email protected]
) by for further information. Include your CV and academic transcript.
The position will remain open until filled.