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Overcoming drug resistance in lung cancer using nano-encapsulated combinatory therapies

  • Full or part time
  • Application Deadline
    Applications accepted all year round
  • Self-Funded PhD Students Only
    Self-Funded PhD Students Only

Project Description

Despite advances in cancer treatment, the development of drug resistance remains a major issue affecting long term patient survival. In parallel, new therapeutic molecules extracted from plants seem attractive due to their ability to act in synergy with conventional chemotherapy and may offer a pathway to restoring sensitivity in resistant cells.

However, to be effective such combinatory therapies would need to be delivered specifically to tumour cells at the same time. This can be achieved using nanomedicines, which, as an added bonus, have also be shown to overcome common mechanisms of drug resistance.

This project provides the opportunity to study how therapeutic combinations and nanomedicines can be exploited to prevent or overcome drug resistance, with a particular focus on lung cancer. This, in turn, will allow for a more informed approach to the design of new drug delivery systems for cancer therapy.

This project should be particularly appealing to students interested in nanotechnology and nutraceuticals and how these can be applied to improve cancer therapy as well as students with an interest in cancer cell biology.

Funding Notes

Applications are invited from self funded students only.

You can search for sources of funding at: View Website

How good is research at University of Birmingham in Clinical Medicine?

FTE Category A staff submitted: 164.15

Research output data provided by the Research Excellence Framework (REF)

Click here to see the results for all UK universities

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