Drug delivery approaches for improved treatment of disease
Applications are welcomed for a project studying novel formulation approaches to overcome the scientific problems associated with drug delivery. There are a number of potential projects in the following areas:
Understanding and control of the solid-state of medicines to improve oral and ocular drug delivery. This will be through the use of co-crystals, amorphous materials and nano-scale crystallisation techniques. The outcome of these projects will be superior understanding of the interplay between the disease state and the solid-state chemistry of the formulation.
Pharmacokinetic study into the problems with oral absorption in the anorexic state. Little is understood about the absorption kinetics of drugs in the chronically anorexic gut, both in anorexia nervosa and other starvation states. This study hopes to address these and allow superior treatment of starved patients in multiple clinical environments (e.g. ITU and outpatient pshchiatric clinics).
These projects would be suitable for a pharmacy or a chemistry graduate with an interest in drug delivery. In addition to gaining laboratory skills, the successful applicant will benefit from the access to the Durham University generic skills training courses.
For entry requirements see https://www.dur.ac.uk/school.health/research/degrees/entry/