• University of Stirling Featured PhD Programmes
  • Northumbria University Featured PhD Programmes
  • Queen’s University Belfast Featured PhD Programmes
  • Staffordshire University Featured PhD Programmes
  • University of East Anglia Featured PhD Programmes
  • University of Glasgow Featured PhD Programmes
  • University of Manchester Featured PhD Programmes
  • University of Southampton Featured PhD Programmes
Brunel University London Featured PhD Programmes
Helmholtz Zentrum München Featured PhD Programmes
University of Leeds Featured PhD Programmes
Imperial College London Featured PhD Programmes
University of Surrey Featured PhD Programmes

The neurophysiological basis of spontaneous fluctuations in neuroimaging signals


Project Description

A technique called blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) can determine levels of different activity in parts of the living human brain and how malfunctions can occur in disease. Furthermore, this technique has been extended to look at communication between brain regions based on the similarity between ongoing signals (‘brain waves’) in connected parts of the brain. However, these magnetic techniques are based on changes in the oxygen content of the blood rather than direct measures of brain activity. They are used because changes in oxygen content can be observed without performing surgery on the brain in human subjects. There is concern, however, because the manifestation of these ongoing brain waves in blood oxygen content is poorly understood and as such the validity of using them to infer communication between brain structures has been questioned. By directly measuring spontaneous brain activity, neuroimaging signals and blood oxygen content at the same time the proposed research hopes to understand the relationships between them and allow this potentially important aspect of neuroimaging to further our understanding of brain function.

Funding Notes

Self funded or sponsored students only. No University funding available.

Related Subjects

How good is research at University of Sheffield in Psychology, Psychiatry and Neuroscience?

FTE Category A staff submitted: 34.45

Research output data provided by the Research Excellence Framework (REF)

Click here to see the results for all UK universities

Email Now

Insert previous message below for editing? 
You haven’t included a message. Providing a specific message means universities will take your enquiry more seriously and helps them provide the information you need.
Why not add a message here
* required field
Send a copy to me for my own records.

Your enquiry has been emailed successfully




Cookie Policy    X