• Staffordshire University Featured PhD Programmes
  • FindA University Ltd Featured PhD Programmes
  • Aberdeen University Featured PhD Programmes
  • University of Pennsylvania Featured PhD Programmes
  • University of Cambridge Featured PhD Programmes
  • University of Tasmania Featured PhD Programmes
University of Tasmania Featured PhD Programmes
University of Liverpool Featured PhD Programmes
Norwich Research Park Featured PhD Programmes
University of Bristol Featured PhD Programmes
National University of Singapore Featured PhD Programmes

Supramolecular hydrogels: from understanding of structure to applications in drug delivery (KHIMYAKU16SF)

This project is no longer listed in the FindAPhD
database and may not be available.

Click here to search the FindAPhD database
for PhD studentship opportunities
  • Full or part time
    Prof Khimyak
  • Application Deadline
    No more applications being accepted
  • Self-Funded PhD Students Only
    Self-Funded PhD Students Only

Project Description

Hydrogels offer a highly biocompatible and tunable solution for drug delivery. Taking into account a significant recent growth in the interest in pharmaceutical systems that can produce such soft solids, it is important to gain a molecular level control of gelation which drive the formation of such supramolecular assembled networks.

This PhD project aims at developing novel soft materials for controlled drug release based on the understanding of intermolecular interactions in gels at different time and length scales. Recent advances in application of such systems in drug delivery relied mostly on empirical trial-and-errors aiming at controlling rheological properties. We will aim at achieving a molecular level understanding of gelation via application of advanced NMR, other spectroscopic and modelling methodologies. The ultimate goal of the project will be to develop NMR/modelling generic strategy in which the final outcome of gelation upon inclusion of a pharmaceutical molecules as a guest or a co-gelator could be predicted at different stages of gelation.

The project presents an excellent opportunity for gaining research skills in several exciting research areas ranging from the development of new materials to their advanced characterisation using modern spectroscopic, thermal and structure determination focused methods. You will contribute to a challenging area of research with considerable industrial relevance and potential to make a significant impact on the development of novel pharmaceutical materials. Through completing the project you will acquire knowledge of a wide range of computational and experimental methods (including different aspects of NMR spectroscopy) chemistry essential in highly competitive academic or industrial environments.

The position is available for graduates in the fields of chemistry, materials science, physics or pharmacy with a degree classification of 2.1 or above (of its equivalent). For further information please contact Prof. Yaroslav Khimyak ([email protected]) as soon as possible.

Funding Notes

This PhD project is offered on a self-funding basis. It is open to applicants with funding or those applying to funding sources. Details of tuition fees can be found at
https://www.uea.ac.uk/study/postgraduate/research-degrees/fees-and-funding

A bench fee is also payable on top of the tuition fee to cover specialist equipment or laboratory costs required for the research. The amount charged annually will vary considerably depending on the nature of the project and applicants should contact the primary supervisor for further information about the fee associated with the project.

References

i) Khimyak et al., Phys Chem Chem Phys, 2015, 24761
ii) Fabian et al.. Mol Pharm, 2015, 2891
iii) Marti-Gastaldo et al., Nature Chemistry, 2014, 343

Share this page:

Cookie Policy    X