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Manufacturing novel artificial enzymes

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  • Full or part time
    Dr L Luk
  • Application Deadline
    No more applications being accepted

Project Description

Applications are invited for a 3-year PhD studentship in chemical biology under the supervision of Dr Louis Luk in the School of Chemistry at Cardiff University.

Project title: Manufacturing novel artificial enzymes

Dr Louis Luk has recently been appointed as a University Research Fellow at the University of Cardiff and is seeking a highly motivated recent graduate to join his research group as he establishes a diverse program, exploring new frontiers in synthetic biology.

We primarily focus on developing a novel approach to generate multifunctional artificial enzymes with organocatalytic activities. The PhD student will develop novel artificial cofactors suitable to catalyse a wide variety of useful chemical reactions. This project is highly multidisciplinary, drawing on tools from organic chemistry, chemical biology, molecular biology and organic chemistry. The PhD student will be able to enjoy learning techniques of organic synthesis, molecular cloning, gene expression, protein purification, chemical synthesis, and the use of various analytical instruments for biophysical characterisation, all of which are routinely used in both academic and industrial laboratories.

Academic criteria: Applicants should have, or expect to obtain, a minimum of an upper second-class honours degree (2:1) or European equivalent and a Masters in Chemistry, Biochemistry or a related discipline.

The successful candidate will also have a strong background in biochemistry and organic chemistry. First-hand experience in a relevant area of chemistry such as enzymology and synthetic chemistry is highly desirable.

A highly motivated and dedicated student will gain a thorough training in synthetic biology and be rewarded with a highly stimulating project that will shape the future of this exciting new research program.

Supervisors: Dr. Louis Luk http://www.cardiff.ac.uk/people/view/122378-luk-louis

Start date: October 2016 (earlier start dates are possible - 1st April 2016, 1st July 2016)

Funding Notes

Residency: This studentship consists of full UK/EU tuition fees, as well as a Doctoral Stipend matching UK Research Council National Minimum (£14,057 p.a. for 2015/16, updated each year).

Please note that this studentship only covers the UK/EU tuition fees. This studentship is open to students of any nationality. Students classified as international for fee purposes have to self-fund the difference between home and international fees.

Cardiff University reserves the right to close applications early should sufficient applications be received.


Interested applicants should send a brief covering letter outlining their experience for the position, as well as their curriculum vitae (including all University course grades to date) and the contact details of at least 2 academic referees to Dr Louis Luk ([email protected]).

Applications will be evaluated on an ongoing basis until the position is filled. Possible start dates are 1st April 2016, 1st July 2016 and 1st October 2016.

How good is research at Cardiff University in Chemistry?

FTE Category A staff submitted: 23.00

Research output data provided by the Research Excellence Framework (REF)

Click here to see the results for all UK universities

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