• University of Leeds Featured PhD Programmes
  • University of Cambridge Featured PhD Programmes
  • Carlos III Health Institute Featured PhD Programmes
  • University of Mannheim Featured PhD Programmes
  • University of Bristol Featured PhD Programmes
  • University of Glasgow Featured PhD Programmes
  • University of Leeds Featured PhD Programmes
  • London School of Economics and Political Science Featured PhD Programmes
University of York Featured PhD Programmes
University of Bristol Featured PhD Programmes
University of Kent Featured PhD Programmes
University of Oxford Featured PhD Programmes
National University of Singapore Featured PhD Programmes

Microstructure design for the delivery of probiotics


Project Description

There is a growing interest in the inclusion of probiotics for foods to deliver live, good bacteria to the human GI tract. In order to achieve the delivery of live bacteria, it needs to be incorporated into the food structure without damage, and then protected from the digestive environment of the mouth, stomach and small intestine (e.g. acidic, enzymatic etc.).

The aim of this project is to investigate ways to incorporate the friendly bacteria into the food microstructure so that they are protected until they arrive at the large intestine. In order to achieve this, the bacteria will need to be inside structures (such as gels, emulsions, and double emulsions) that retain their viability while the food is being stored, and reduce the impact of the digestive processes.

Areas to be investigated:

• Ability to include live bacteria into food microstructures, i.e. build the food microstructure in a way that does not cause stress to the cells. Investigate a range of different hydrocolloids that can be used, and different processing parameters (e.g. temperature control, shear rates etc.) for successful cell survival.
• Investigate the effect of the bacteria on the properties of the hydrocolloid gel system (e.g. rheology).
• Design food microstructures that protect the cells in both storage and digestion.
• Investigate how the microstructures are affected by the digestive environment, and how the cells can be delivered to the microflora, so that they can be retained in the large intestine.

Funding Notes

Funding available for EU/UK students only. Applicants should have obtained an Honours Degree or equivalent at 2.1 or above in Chemical Engineering, Chemistry, or related disciplines.

How good is research at University of Birmingham in Aeronautical, Mechanical, Chemical and Manufacturing Engineering?
Chemical Engineering

FTE Category A staff submitted: 32.50

Research output data provided by the Research Excellence Framework (REF)

Click here to see the results for all UK universities

Email Now

Insert previous message below for editing? 
You haven’t included a message. Providing a specific message means universities will take your enquiry more seriously and helps them provide the information you need.
Why not add a message here
* required field
Send a copy to me for my own records.
Email Sent

Share this page:

Cookie Policy    X