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Mathematical modelling to support the delivery of Q-POC(TM), a novel, handheld malaria diagnostic and drug resistance screen

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  • Full or part time
    Dr Laith Yakob
  • Application Deadline
    No more applications being accepted
  • Competition Funded PhD Project (European/UK Students Only)
    Competition Funded PhD Project (European/UK Students Only)

Project Description

(Co-supervisor: Dr Henry Staines at St George’s University of London).

Two of the biggest hurdles to malaria elimination are 1) identification of cases in low-transmission settings (especially in resource-limited regions), and 2) resistance of the parasites to chemotherapy. Q-POC(TM) is a novel, handheld tool under current development that simultaneously diagnoses malaria and screens for drug resistant parasites (www.nanomal.org). Results are available in 10-15 minutes allowing for rapid detection and appropriate treatment. Through a secure mobile data connection, the emergence and spread of drug resistance markers can be tracked in real time with GPS.

Potentially yielding large and extremely rich datasets, it is paramount to make best use of these data to 1) improve disease and resistance status surveillance; 2) provide early warning of epidemics and new drug-resistant parasite emergence; 3) tailor control more locally; and 4) inform strategic utilisation of this technology for maximum benefit.

Mathematical models have become increasingly important components in disease control strategy (especially so in the context of malaria). However, strategizing the consolidation and maintenance of elimination, and the prevention and management of drug resistance are major research shortage areas that require accelerated development.

Funding Notes

Only UK, or non-UK resident EU nationals, are eligible for funding.
Applicants should be outstanding, highly motivated and have backgrounds in medical, biological or mathematical sciences.
Applicants interested in the full funding will have to participate in a competitive selection process.
Successful studentship applications will result in a student stipend of £16,057.
Applications must be submitted by 31st January 2016. Application details are found here: http://mrc-lid.lshtm.ac.uk/application-guidance-information/
This project can also be undertaken as a self-funded project, either through your own funds or through a body external to the London School of Hygiene & Tropical Medicine. Self-funded applications are accepted year-round.

How good is research at London School of Hygiene & Tropical Medicine in Public Health, Health Services and Primary Care?

FTE Category A staff submitted: 257.16

Research output data provided by the Research Excellence Framework (REF)

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