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Optimisation of mesenchymal stem cell interactions with photoactive materials for dental and orthopaedic repair


Project Description

Supervisors: Drs WM Palin, RM Shelton, PR Cooper

For repair and replacement of dental tissue, “photoactive” biomaterials offer significant benefits since light curing provides a fully controllable setting mechanism of a single paste system, which requires no mixing by the surgeon. As such, photoactive biomaterials for orthopaedic application are of great interest and are currently being developed in our laboratory. Unfortunately, the resin chemistry used for such photoactive materials and the nature of the light-cured free-radical polymerization reaction may lead to an undesirable biological response in host tissues.

The aim of the current project is to investigate the effect of material components in model photoactive resin formulations on setting reactions and to improve the interaction at the biomaterial-tissue interface.

To find out more about studying for a PhD at the University of Birmingham, including full details of the research undertaken in each school, the funding opportunities for each subject, and guidance on making your application, you can now order your copy of the new Doctoral Research Prospectus, at: http://www.birmingham.ac.uk/students/drp.aspx

Funding Notes

We have a thriving international Researcher community and encourage applications from students of any nationality able to fund their own studies (i.e. through Government scholarship schemes, self-funding), or who wish to apply for their own funding (e.g. Commonwealth Scholarships, Islamic Development Bank International PhD Scholarships, China Scholarship Council).

How good is research at University of Birmingham in Allied Health Professions, Dentistry, Nursing and Pharmacy?

FTE Category A staff submitted: 15.90

Research output data provided by the Research Excellence Framework (REF)

Click here to see the results for all UK universities

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