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Cellular regulation of and by the Hippo pathway: Cancer and Regeneration

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  • Full or part time
    Dr Hansen
  • Application Deadline
    No more applications being accepted
  • Funded PhD Project (European/UK Students Only)
    Funded PhD Project (European/UK Students Only)

Project Description

In recent years, the Hippo pathway has become widely recognized as playing a significant role in
stem cell and cancer biology (1). Your research will focus on the cellular regulation of and by the
Hippo Pathway and will utilize a variety of techniques to address key outstanding questions in
the field (2). These techniques include a combination of biochemical, genome editing (CrispR) and
microscopy based methods for both mammalian cell culture systems, as well as the zebrafish.
The PhD studentship is available in 2016 and you will be based at the MRC-CIR. The position is
open to outstanding students with a strong personal drive and interest in cell signaling and cell
biology. The emphasis in the newly established lab is on generating a focus on teamwork
and a dedication to addressing interesting high-impact questions about the Hippo pathway.
We aim to create an intellectually stimulating, fun and productive lab environment to work in.

Applicants should email a short personal statement regarding their research interests,
experience, and reasons for applying. Please also include potential starting dates, along with a
CV. Applicants should also include contact details for two potential referees, and explain how
they know the applicant. The position is in the first instance open for applications until February
15th (or until suitable applicants have been identified). Thereafter, shortlisting and interviews
will take place. Flexible starting dates will be available for the successful applicant.

The University of Edinburgh is known for its world leading research, and the university is
located in a vibrant historic city that continually scores highly in livability and has easy access to
the stunning Scottish outdoors.

For further information about this post, please contact:
Dr. Carsten Gram Hansen, [email protected]
www.cir.ed.ac.uk/investigator/dr-carsten-gram-hansen

Funding Notes

Applicants should hold at least an upper second class degree or equivalent in
biomedical sciences, and should be an EU citizen (due to funding body requirements).
The applicant should also have good interpersonal skills and be fluent in English.

References

1 Moroishi T, Hansen CG, Guan KL. The emerging roles of YAP and TAZ in cancer. Nature reviews Cancer 2015; 15:73-79.
2 Hansen CG, Moroishi T, Guan KL. YAP and TAZ: a nexus for Hippo signaling and beyond. Trends in cell biology 2015.

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