Combining genetic and modelling approaches to understanding vascular development in Arabidopsis (Durham)
Cell division and differentiation occur in a highly ordered manner in plant vascular tissue, making it an excellent model for studying developmental biology. Plant vascular development is under tight genetic control, and is influenced by a signalling mechanism that includes a ligand, TDIF and receptor known as PXY. TDIF-PXY signalling controls cell division, differentiation and tissue organisation. We have shown that manipulating TDIF-PXY signalling can lead to increases in plant productivity. A number of genes have been identified that respond to PXY signalling to control vascular development. The student will use a combination of genetics, molecular biology and systems biology approaches to characterise how these factors interact to coordinate plant development.
For further information see the website: https://www.dur.ac.uk/biosciences/
Please submit a full CV and covering letter directly to [email protected]
This is a 4 year BBSRC studentship under the Newcastle-Liverpool-Durham DTP. The successful applicant will receive research costs, tuition fees and stipend (£14,057 for 2015-16). The PhD will start in September 2016. Applicants should have, or be expecting to receive, a 2.1 Hons degree (or equivalent) in a relevant subject. EU candidates must have been resident in the UK for 3 years in order to receive full support. There are 2 stages to the application process.
Etchells, J. P., Mishra, L. S., Kumar, M., Campbell, L. and Turner, S. R. (2015). Wood formation in trees is increased by manipulating PXY-regulated cell division. Current Biology 25:1050.