Epigenetic control of virulence in the fungal plant pathogen, Zymoseptoria triciti (Newcastle)
This project will investigate the role that epigenetic controls play in regulating the virulence of the fungal plant pathogen, Zymoseptoria triciti. Z. triciti is the causative agent of Septoria tritici blotch (STB), a serious worldwide disease of wheat which can result in up to a 50% reduction in yields. Recent evidence suggests that the proper expression of Z. triciti pathogenicity genes is co-ordinated by reprogramming of heterochromatic regions of the genome. Therefore this project will utilise a range of molecular biological approaches to determine how disruption to heterochromatin assembly affects the expression of pathogenicity genes and the virulence of Z. triciti.
For further information see the website: http://www.ncl.ac.uk/camb/
Please submit a full CV and covering letter directly to [email protected]
This is a 4 year BBSRC studentship under the Newcastle-Liverpool-Durham DTP. The successful applicant will receive research costs, tuition fees and stipend (£14,057 for 2015-16). The PhD will start in September 2016. Applicants should have, or be expecting to receive, a 2.1 Hons degree (or equivalent) in a relevant subject. EU candidates must have been resident in the UK for 3 years in order to receive full support. There are 2 stages to the application process.
Gal C, Murton HE, Subramanian L, Whale AJ, Moore KM, Paszkiewicz K, Codlin S, Bähler J, Creamer K, Partridge JF, Allshire RC, Kent NA and Whitehall SK (2015) Abo1, a conserved bromodomain AAA-ATPase, maintains global nucleosome occupancy and organization. EMBO Reps (in press)