Development of 3-dimensional cell culture for integrated modelling of cells and tissues (Liverpool, iCASE award)
Our understanding of the biology of the cell has been informed by decades of studies of cells growing in two-dimensional cell layers. Real biological systems however are 3-dimensional and it has become clear that there are significant differences in terms of gene expression and response to treatments. This project explores new opportunities for growing and imaging cells in 3 dimensions and their impact on the biology of the cell. It offers an array of opportunities to the student for scientific development and close collaboration between an academic and industrial partnership (http://www.aureliabio.com/). The extensive multidisciplinary nature of the project would involve interaction with biologists, materials scientists, biophysicists, pharmacologists and industrial biotechnologists and would suit an ambitious applicant with a strong interest in technology development and biotechnology.
For further information see the website: https://www.liverpool.ac.uk/integrative-biology/ and blog post https://raphazlab.wordpress.com/2016/01/15/looking-for-a-beautiful-phd/
Please submit a full CV and covering letter directly to [email protected]
This is a 4 year BBSRC iCASE studentship under the Newcastle-Liverpool-Durham DTP. The successful applicant will receive research costs, tuition fees and stipend (£14,057 for 2015-16). The PhD will start in September 2016. Applicants should have, or be expecting to receive, a 2.1 Hons degree (or equivalent) in a relevant subject. EU candidates must have been resident in the UK for 3 years in order to receive full support. There are 2 stages to the application process.
Nanoparticles for imaging, sensing, and therapeutic intervention; Bogart, LK, Pourroy, G, Murphy, CJ, Puntes, V, Pellegrino, Rosenblum, D, Peer, D and Lévy R (2012) ACS Nano 8, 3107-3122