Evolution of Adaptor Molecules for Antigen-binding-receptors
During evolution of the adative immune system, antigen-binding-receptor molecules developed that are able to recognise antigens but do not carry signalling transmitting capacity. Adaptor molecules evolved that transmit signals through the antigen binding receptors into the antigen specific cells. The aim of the project is to understand the evolutionary path of the development of antigen binding receptors and the associated adaptor molecules.
This project requires skills in computer programming, understanding of bio-informatics programs, understanding of signalling cascades in immune cells.
This project has a Band 1 fee. Details of our different fee bands can be found on our website. For information on how to apply for this project, please visit the Faculty of Biology, Medicine and Health Doctoral Academy website. Informal enquiries may be made directly to the primary supervisor.