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The role of coronin in platelet cytoskeletal changes and cardiovascular function.

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  • Full or part time
    Dr F Rivero
    Prof K Naseem
  • Application Deadline
    No more applications being accepted
  • Funded PhD Project (Students Worldwide)
    Funded PhD Project (Students Worldwide)

About This PhD Project

Project Description

A British Heart Foundation funded PhD position is available for an outstanding student to study the signal transduction pathways that regulate the function of blood platelets. It is based at the Hull campus of Hull York Medical School supervised by Dr Francisco Rivero and Professor Khalid Naseem.

In this project we will investigate the role of the cytoskeleton protein coronin in the regulation of platelet adhesion, activation and aggregation and its potential influence on development of cardiovascular disease. The studentship provides an excellent opportunity to receive training in basic cell and molecular biology techniques (immunoblotting/immunoprecipitation, flow cytometry, fuorescence/confocal microscopy, proteomics) in the study of cellular signal transduction. The student will join a research team that utilises multidisciplinary approaches to identify new mechanisms regulating platelet function and determine if these newly identified mechanisms can be targets for prevention and treatment of arterial thrombosis.

Informal enquiries should be addressed to Dr. Francisco Rivero ([Email Address Removed]), Prof. Khalid Naseem ([Email Address Removed]) or Mrs. Helen Procter ([Email Address Removed]).

The post is a full-time studentship for 3 years, depending on satisfactory progress, funded by the British Heart Foundation. It includes stipend at an enhanced rate, tuition fees and bench fees for a UK/EU student. The start date is open to negotiation (earliest 1 April 2016). The deadline for applications is 29 February 2016.

Applicants should hold First or Upper Second Class Honours degree or equivalent, and an MSc (with distinction) in biochemistry, biomedical sciences, pharmacology or a related area of biological sciences. The position is open only to EU/UK applicants. Applicants for whom English is not their native language will need to demonstrate adequate proficiency (IELTS 7.0).

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