This project is no longer listed in the FindAPhD
database and may not be available.
The 3 year MRC funded studentships are open to outstanding UK science graduates wishing to pursue a career in Reproductive Health. The studentship will cover fees at the UK/EU rate and a minimum stipend as directed by the MRC.
This research project will be in direct competition with 7 other projects currently on offer at the MRC-CRH. Usually the project with the best applicant/s will be awarded the funding. The funding is available to UK graduates who can demonstrate ordinary residence in the UK as defined at through the link below.
1. N. Tokushige, R. Markham, P. Russell, I. S. Fraser, Nerve fibres in peritoneal endometriosis. Hum Reprod 21, 3001-3007 (2006).
2. X. Cao, D. Yang, M. Song, A. Murphy, S. Parthasarathy, The presence of endometrial cells in the peritoneal cavity enhances monocyte recruitment and induces inflammatory cytokines in mice: implications for endometriosis. Fertil Steril 82 Suppl 3, 999-1007 (2004).
3. T. A. Wynn, A. Chawla, J. W. Pollard, Macrophage biology in development, homeostasis and disease. Nature 496, 445-455 (2013).
4. L. C. Davies, S. J. Jenkins, J. E. Allen, P. R. Taylor, Tissue-resident macrophages. Nat Immunol 14, 986-995 (2013).
5. E. L. Gautier, T. Shay, J. Miller, M. Greter, C. Jakubzick, S. Ivanov, J. Helft, A. Chow, K. G. Elpek, S. Gordonov, A. R. Mazloom, A. Ma'ayan, W. J. Chua, T. H. Hansen, S. J. Turley, M. Merad, G. J. Randolph, Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages. Nat Immunol 13, 1118-1128 (2012).
6. S. Gordon, P. R. Taylor, Monocyte and macrophage heterogeneity. Nat Rev Immunol 5, 953-964 (2005).
7. J. W. Pollard, Trophic macrophages in development and disease. Nat Rev Immunol 9, 259-270 (2009).
8. L. V. Tran, N. Tokushige, M. Berbic, R. Markham, I. S. Fraser, Macrophages and nerve fibres in peritoneal endometriosis. Hum Reprod 24, 835-841 (2009).
9. E. Greaves, J. Temp, A. Esnal-Zufiurre, S. Mechsner, A. W. Horne, P. T. Saunders, Estradiol Is a Critical Mediator of Macrophage-Nerve Cross Talk in Peritoneal Endometriosis. Am J Pathol, (2015).
10. E. Greaves, F. Collins, A. Esnal, S. Giakoumelou, A. W. Horne, P. T. Saunders, Estrogen receptor (ER) agonists differentially regulate neuroangiogenesis in peritoneal endometriosis via the repellent factor SLIT3. Endocrinology, en20141086 (2014).
11. E. Greaves, K. Grieve, A. W. Horne, P. T. Saunders, Elevated peritoneal expression and estrogen regulation of nociceptive ion channels in endometriosis. J Clin Endocrinol Metab, jc20142282 (2014).
12. E. Greaves, F. L. Cousins, A. Murray, A. Esnal-Zufiaurre, A. Fassbender, A. W. Horne, P. T. Saunders, A novel mouse model of endometriosis mimics human phenotype and reveals insights into the inflammatory contribution of shed endometrium. Am J Pathol 184, 1930-1939 (2014).
FTE Category A staff submitted: 206.93
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