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Dissecting the molecular interactions underpinning Spindle Assembly Checkpoint (SAC) signalling

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  • Full or part time
    Dr Bolanos-Garcia
  • Application Deadline
    No more applications being accepted
  • Competition Funded PhD Project (European/UK Students Only)
    Competition Funded PhD Project (European/UK Students Only)

Project Description

Competitive three year full time studentship in the Department of Biological and Medical Sciences

Project Title : Dissecting the molecular interactions underpinning Spindle Assembly Checkpoint (SAC) signalling.

Main supervisor Dr Victor Bolanos-Garcia

Eligibility:Only open to UK/EU applicants (who must be permanently resident in UK/EU)


Start date: 19th September 2016

Bursary: £14057 pa for academic year 2016/17 & fees

Closing date: 21st February 2016

Applicants should be of the highest quality and capable of submitting a PhD thesis within 3 years. Requirement a good Honours degree (2.1 or equivalent).

EU applicants must have a valid IELTS Academic test certificate minimum score level 6 in each of the four areas of reading, writing, listening and speaking with overall minimum score 7.0 issued since the 23rd April 2015 by an approved test centre please see web site below. Or an undergraduate degree awarded by a recognised UK university within the last two years.

https://www.gov.uk/government/publications/guidance-on-applying-for-uk-visa-approved-english-language-tests


Project summary


The project involves a multidisciplinary approach to the uncovering and the functional and structural characterisation of protein-protein interactions that ensure the accurate and timely segregation of the genetic material in higher organisms. The PhD research project will foster skills in cell biology, protein biochemistry, protein biophysics and X-ray protein crystallography methods and involves extensive collaboration with research teams at the Universities of Oxford and Cambridge, the Imperial College London and with overseas collaborators in Canada and France.

The appointed individual will have the opportunity to train undergraduate students in state-of-the-art molecular biology, biochemical and biophysical techniques; to regularly disseminate her/his work at national and international meetings and to participate in outreach activities such as Science Festivals and talks in schools.

As part of your training you will be required to assist in demonstrating on undergraduate practicals during semesters without further remuneration.

Please note that any successful applicant may be subject to a DBS search once they enrol in view of outreach activities involving schools. In view of checking procedures they will be required to exhibit a current passport - -https://www.gov.uk/disclosure-barring-service-check

Further information on the project please contact
Dr Victor Bolanos-Garcia e-mail address [email protected]

How to apply

Please complete the Application Form, which you can download from

http://www.hls.brookes.ac.uk/images/research/phd-studentship-application-form-jan-14.doc


With your application please enclose a CV and scanned copy of your degree certificates and transcripts and letter from awarding body plus two signed academic references. Additionally if appropriate a valid IELTS Academic test score certificate.


Please carefully note that applications only accepted by e-mail to the following address:
[email protected]



PLEASE NOTE THAT YOU MUST NOT SEND ANY QUERIES, APPLICATION, CV or OTHER DOCUMENTS VIA FINDAPHD


Funding Notes

Start date: 19th September 2016

Bursary: £14057 pa for academic year 2016/17 & fees

Closing date: 21st February 2016

Requirement a good Honours degree minimum 2.1 from a UK university or acceptable equivalent from a recognised university.

EU applicants must have a valid IELTS Academic test certificate minimum score level 6 in each of the four areas of reading, writing, listening and speaking with overall minimum score 7.0 issued since the 23rd April 2015 by an approved test centre please see web site below. Or an undergraduate degree awarded by a recognised UK university within the last two years.

https://www.gov.uk/government/publications/guidance-on-applying-for-uk-visa-approved-english-language-tests



References

Recent publications:

• Kapanidou M, Lee S, and Bolanos-Garcia V. M. “BubR1 kinase: protection against aneuploidy and premature aging”. Trends in Molecular Medicine 2015, 21: 364-372.

• Lischetti T, Zhan G, Sedgwick G.G., Bolanos-Garcia V.M., Nilsson J. ”The internal Cdc20 binding site in BubR1 facilitates both spindle assembly checkpoint signalling and silencing”. Nature Communications 2014, 5:5563.

• Ghongane P, Kapanidou M, Asghar A, Elowe S, Bolanos-Garcia VM. “The KNL1 hub: a dynamic kinetochore rendezvous”. J Cell Sci. 2014, 127:3415-23.

• Lee S, Bolanos-Garcia VM. “The dynamics of signal amplification by macromolecular assemblies for the control of chromosome segregation”. Frontiers in Physiol. 2014, 5:368.

How good is research at Oxford Brookes University in Biological Sciences?

FTE Category A staff submitted: 25.60

Research output data provided by the Research Excellence Framework (REF)

Click here to see the results for all UK universities
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