PhD-student position: Transgenic mouse models for Alzheimer’s disease

A PhD student position in the field of Alzheimer’s disease research is currently being offered at the Institute of Pathology, University Hospital Basel, Switzerland. The project aims at uncovering pathophysiological disease mechanisms with transgenic mice.

We are looking for a highly motivated, science-driven person with:
- A Master’s degree in neuroscience, biochemistry, biology or a related discipline, preferentially obtained from a leading European university.
- Solid hands-on experience in protein-biochemistry (e.g. protein extraction, gel electrophoresis, western blotting, immunoprecipitation, ELISA).
- Good communication and English language skills.

Additional expertise and/or knowledge in the following areas would be a plus:
- Histology: tissue preparation, staining (histochemical, immunohistochemical, immunofluorescence) microscopic analysis and image quantification.
- Molecular biology: gene cloning, protein expression, PCR, mouse genotyping.
- Laboratory animal experimentation: mouse colony management, handling, perfusion and in vivo experiments (FELASA B level).

Recent publications of our lab include:
- Co-expression of truncated and full-length tau induces severe neurotoxicity, Mol Psychiatry 2016.
- Amyloid-beta in the cerebrospinal fluid of APP transgenic mice does not show prion-like properties, Curr Alzheimer Res 2015.

If you are excited about neurodegeneration research and match the above qualifications we look forward to receiving your electronic application, including information on your previous research experiences.