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  How do diets rich in broccoli prevent prostate cancer progression? (MITHENF17BCS)


   Graduate Programme

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  Prof R Mithen  No more applications being accepted  Funded PhD Project (Students Worldwide)

About the Project

Intake of cruciferous vegetables such as broccoli is negatively correlated with incidence of prostate cancer. On the Norwich Research Park cultivars of broccoli have been developed that accumulate enhanced levels of sulphur-containing compounds with potential anti-cancer activity, and are being used in clinical intervention trials with men who have organ-confined prostate cancer. This studentship will explore how these plant metabolites affect gene expression and metabolism in the prostate cancer tumour microenvironment to inhibit the growth of cancerous clones. The research will involve the use of cell and ex vivo human tissues models and possibly a short term human intervention study. The appointee will acquire a range of skills in molecular biology and biochemistry and work closely with clinical colleagues. The research will lead to further development of functional food products that may be helpful in reducing prostate cancer progression. For further details please contact [Email Address Removed]

For further information and to apply, please visit the ’How to Apply’ page on our website:
http://students.ifr.ac.uk/how-to-apply/

Funding Notes

This project is awarded with a 4 year Norfolk Cancer Charity BIG C PhD studentship. A stipend will be provided for each year of the studentship (2016/7 rate will be £14296.00). Tuition fees are covered for UK/EU rate. International students are eligible for funding but will need to find their own support to cover the extra tuition fees chargeable to overseas students. (Tuition fee rates for 2016/7 for UK/EU students is £4121.00, for international students it is £17000.00). Research training support funding is available in a well funded laboratory.