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  The Development of Green Electrosynthesis of Organic Molecules


   School of Chemistry

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  Dr AM Jones  Applications accepted all year round  Self-Funded PhD Students Only

About the Project

This PhD project will evaluate the potential of an electrochemical cell to perform selective metal-free oxidations of organic molecules versus the traditional synthetic route. Such approaches are yet to be realised providing a greener approach to performing chemical transformations for the preparation of pharmaceuticals and industrial materials.

This PhD project will focus on developing, optimizing and evaluating the effectiveness of synthetic organic electrochemistry. The primary objectives will be to demonstrate the use of graphene electrodes to replace precious metal electrodes and the use of ionic liquids as green reaction solvents to replace standard organic solvents. Evaluation of the developed electrochemical set-up with the “best known” electrochemical cells will inform the development of your system. Application of the developed system to important reactions for the pharmaceutical industry will be demonstrated using single electrons as a “traceless oxidant”.

For more information about the research group please visit: www.jonesgroupresearch.wordpress.com

Funding Notes

SPECIFIC REQUIREMENTS OF THE PROJECT
Good Honours Degree (2:1 or above or EU equivalent) in Chemistry or Chemical Engineering. For international candidates (average marks > 60% and evidence of your proficiency in the English language, if applicable). The PhD position is open to self-funding UK or international students only.

References

Alfonso-Súarez, P., Kolliopoulos, A. V., Smith, J. P., Banks, C. E., Jones, A. M. “An Experimentalists Guide to Electrosynthesis: The Shono Oxidation” Tetrahedron Lett. 2015, 56, 6863-6867. (Highlighted in the Organic Chemistry Portal 2017)

Jones, A. M., Banks, C. E. “The Shono-type electroorganic oxidation of unfunctionalised amides. Carbon-carbon bond formation via electrogenerated N-acyliminium ions” Beilstein J. Org. Chem., 2014, 10, 3056–3072. (This article is part of the Thematic Series “Electrosynthesis”)

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