Throwing Genomic light into tunnel vision

Supervisor: Dr. Arijit Mukhopadhyay
(the project will be carried out in collaboration with The Manchester Royal Eye Hospital)

Proposal: Glaucoma is the largest cause of irreversible blindness. It is usually painless and thus detected only when the majority of the peripheral vision is lost resulting in a tunnel vision. Glaucoma is a common disease affecting 1% of the general population. It is largely inherited but rarely caused by a single gene making the quest challenging and exciting. Research so far can explain less than 10% of the underlying genetic causes for the disease.

Students interested in this project will get a thorough understanding of complex disease genetics and will learn latest wet-lab and analysis strategies to perform genome-wide experiments. This position is open for students interested in both dry-lab and/or wet-lab. Existing knowledge of analysing next generation sequencing data will be an added advantage. This project has the potential of translating genetic diagnostic tests for better disease management.

For more information on research within the School of Environment and Life Sciences please visit the School research website www.salford.ac.uk/environment-life-sciences/research