EPSRC-funded PhD project to investigate the Non-Equilibrium Statistical Physics of Stem Cell Differentiation

The aim of the proposed project is to build on recent advances in molecular systems biology and non-equilibrium statistical physics to describe gene regulation networks and their dynamics over the course of the differentiation process. Statistical physics can describe e.g. the states of regulatory networks corresponding to certain cell-types or fates (e.g. embryonic stem cell vs neural progenitor); non-equilibrium statistical physics goes beyond this and allows us to investigate how these networks are remodeled over the course of differentiation, development more generally, or in response to environmental stimuli.

This project would suit candidates with experience and interests in computational and theoretical physics, applied mathematics, statistics, or computational biology. A masters degree, e.g. in bioinformatics, systems biology, computational physics or statistics, is required. There is tremendous scope for applying concepts from statistical physics in biology, and this project, which will involve collaborations with the groups of Heike Siebert (FU Berlin) and Alfonso-Martinez-Arias (Cambridge), provides an ideal opportunity for enthusiastic young scientists wishing to conduct multi-disciplinary research.
ppHow to apply:
Please email Professor Michael Stumpf ([Email Address Removed]) and include in your application:
• A cover letter
• Your CV
• Your transcript (available to-date)
• At least two references sent directly to Professor Stumpf from the referees
Full applications made before 10th May 2017 will be considered at any time.
Funding and eligibility:
Eligibility criteria: Imperial College normally requires applicants for 3-year PhD positions to already have a Masters degree, at Merit level or above, by the start of the project. The BSc degree must be at 2:1 level or better in a relevant subject area. Studentships funded by UK Research Councils generally apply only to UK students or EU students who have been in the UK for at least 3 years prior to the start of the PhD.