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  Neurobiology of the hair follicle: using patch clamp to investigate the electrophysiological properties of cells in the human hair follicle


   Department of Bioengineering

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  Dr C Higgins, Dr A Kozlov  Applications accepted all year round

About the Project

We invite applications for an EPSRC iCASE PhD studentship in the Higgins and Kozlov labs in the Department of Bioengineering at Imperial College London for an October 2017 entry. The PhD position is fully funded for UK/EU candidates. The position is supervised by Dr Claire Higgins (www.higginslab.org) and Dr Andrei Kozlov (http://www.kozlovlab.com/), both in the Department of Bioengineering, and is a collaborative project with Proctor and Gamble.

The focus of this research will be on the neurobiology of the hair follicle. The hair follicle is a key player in somatosensation. It is innervated by mechanically sensitive cutaneous sensory neurons that are activated by light touch. Despite our understanding of mechanosensation in murine skin, less is known about mechanosensation in human skin, especially across body sites that differ with regard to their hair type (e.g., beard vs scalp hair). This studentship will involve using and developing imaging techniques to improve our understanding of the neural networks innervating hair follicles in the human skin. In addition to wide-field and confocal microscopy (e.g., for calcium imaging), the successful candidate will use patch clamp to investigate the electrophysiological properties of cells in the human hair follicle.

Candidates interested in neurobiology of the skin, somatosensation, mechanobiology, imaging, and electrophysiology should apply. Applicants should have prior experience of patch clamp. Applicants should have an MEng, MSc or MRes (or equivalent research experience and qualification) in bioengineering, physics, biological or natural sciences.
We are looking for people with good communication skills but most importantly with enthusiasm for experimental interdisciplinary research and interested to learn new techniques and approaches.

To apply for this position, please email a single PDF file including: a brief cover letter describing your interests and research experience, your CV, and names and contact information of two references to Dr Claire Higgins ([Email Address Removed]) with the subject line “HairNeuro-PhD”. Applications will be accepted until the position is filled.



Funding Notes

We invite applications for an EPSRC iCASE PhD studentship in the Higgins and Kozlov labs in the Department of Bioengineering at Imperial College London for an October 2017 entry. The PhD position is fully funded for UK/EU candidates. The position is supervised by Dr Claire Higgins and Dr Andrei Kozlov, both in the Department of Bioengineering, and is a collaborative project with Proctor and Gamble.

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