Self-assembly of Novel L-Carnitine Amphiphiles

PhD Studentship in Biological Physics

Anticipated start date for project: September 2017.
Closing date for applications: The application process remains open until a suitably qualified candidate is successfully recruited.
Information about the projectA PhD studentship is available starting from September 2017 in Biological Physics, the School of Physics and Astronomy, University of Manchester. The studentship is funded by EPSRC, with a CASE top up from Lonza. The Manchester branch of Lonza harnesses science and technology to create processes and products that support safer and healthier living and that enhance the overall quality of life.

L-carnitine amphiphiles could offer attractive surface activity and solution aggregation, but there is so far no study aimed at elucidating their physiochemical properties. Given the potential health and medical benefits from these molecules, this project is set to undertake a systematic study of their surface and interfacial adsorption and solution aggregation by a range of physical techniques including neutron reflection and scattering. The student will learn not only how to undertake key physical measurements such as neutron reflection and scattering, but also how to analyse experimental data and come up with appropriate models that could interpret the structural implications. This work will thus contribute to the development of the theoretical basis about how to control interfacial processes and interactions.

The student will base his/her research at Manchester but will undertake research and training at neutron facilities (RAL, ILL) and Lonza Manchester. Lonza will provide full support and training on sample synthesis and purification and related characterisations. The project thus provides a unique training opportunity for the student to learn how to link leading scientific research to technology innovations.

Qualifications applicants should have/expect to receive:
The successful candidate will have or expect to obtain a first or upper second class degree or equivalent in a relevant degree (e.g. MPhys, MSci, MChem, MPharm) in science, engineering and bioscience. Those with experimental/computational skills and enthusiasm for research and innovation are encouraged to apply.

Amount of funding available and eligibility:
The project is funded for the maximum period of 3.5 years. No prior experience of neutron research or bioscience is required as a full package of training and support will be provided.

Contact for further information:
[Email Address Removed] or drop in to Room 3.14, Schuster Building on Manchester campus.

Project Supervisor: Prof Jian R Lu (Manchester Biological Physics).

How to apply: standard procedure by following the online application from www.manchester.ac.uk, but informal enquiry should be directed to Prof Jian R Lu.