Can dampening inflammation during pregnancy improve offspring outcomes later in life?

Unravelling how early life in the womb adversely affects the future disease risk of the child is critical to reversing the obesity and diabetes epidemic. The mechanisms which ‘program’ an individual to a life-long increased risk of metabolic dysfunction remain largely unknown. By examining traditional developmental programming models within the context of immune deficiency we can further the mechanistic understanding of the early life triggers which predispose individuals to non-communicable disease and potentially revolutionise the way we tackle adult disease.

Objective:

Using a range of animal models, biochemical, cell culture and molecular techniques this project aims to provide insight into the mechanisms which contribute to the developmental origins of health and disease.


What we are looking for in a successful candidate:

- First class honours degree in a relevant biological subject.
- Previous experience with molecular and/or cell culture techniques is desirable but not essential.
- Self-motivated.
- Attention to detail.

This project will provide training in a wide range of skills including:

- Gene expression profiling
- Protein analysis
- Histology
- Primary tissue culture
- Scientific writing



Funding notes:

If you have a GPA of 8.0 or more and you completed your most recent qualifying programme at a New Zealand university, you’ll be supported throughout your PhD study by a University of Auckland Doctoral Scholarship, which gives you a NZ$27,300 tax-free stipend (plus tuition fees) every year for three years. If your GPA is less than 8.0, there may still be scholarships available - you can discuss this with your potential supervisor or the academic director.

There are no international fees for PhD students: as long as you live in New Zealand during your period of enrolment you will pay the same as New Zealanders.