Prof Steven Siciliano, Prof M Hecker
No more applications being accepted
Funded PhD Project (Students Worldwide)
About the Project
A team of students, technicians, and post-doctoral fellows is being assembled to work with five toxicology professors, the local regulator, consulting company, and site owner, to develop innovative approaches to assess the human health chemical risk associated with a complex operating site that contains a complex, unresolved mixture in groundwater and soil. The students and fellows will work at the University of Saskatchewan Toxicology Group, one of the largest groups of its kind in North America.
This PhD project will estimate the risk posed to humans by a complex mixture of toxicants by comparing the response of cells lines such as IPEJ1 and HEPG2 to the toxicant mixture to the same cell lines’ response to a collection of 30 reference toxicants. These reference toxicants already have animal data associated with them, and thus we will be able to read across from our mixture to these reference toxicants to infer safe exposure levels for humans. Candidates should have a strong background in toxicology and/or mammalian biochemistry, as well as interest in biometrics and/or chemometrics. The project will involve the candidate working closely with three other PhD students who are working on fish and murine models of toxic action for this complex mixture. In addition, the project involves this candidate working closely with practicing risk assessors and a research associate well versed in analytical toxicology.
Only candidates with previous publications will be considered for this position.
Funding Notes
This is a fully funded position that offers students a full stipend for a 3 year period. Tuition is not covered in the stipend and must be covered by the students. Typically, students are eligible for internal scholarships that offset most of the tuition. Outstanding students, students with more than a 85% average and publications, are eligible for substantial additional scholarships.
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