Atomic resolution study of transient structures and complexes of Microtubule Associated Protein 2c

Microtubule Associated Protein 2c (MAP2c) is an intrinsically disordered protein important for development of nerve cells, expressed prenatally in dendrites. Dynamics, interactions, and structural features of MAP2c has been studied previously in our group. The aim of the thesis is to use nuclear magnetic resonance spectroscopy, X-ray crystallography, and other relevant techniques to characterize with atomic resolution structures of MAP2c present in complexes with interacting partners and transiently in solution.

Applicants who wish to pursue a degree at the CEITEC PhD programme must hold the equivalent of a Master’s degree (MSc) in similar field (four or five year undergraduate degree). The application can be submitted before obtaining the Master’s degree, however, the applicant should obtain the degree within five month after the application deadline.

Detail information about the admission procedure available at http://ls-phd.ceitec.cz/information-for-applicants/
All general enquiries should be directed to Olga Krizova ([Email Address Removed]). Scientific inquiries can be addressed to the supervisor
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