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  The role of cytokinin-inducible EXPANSINs in the control of cell wall properties and development in Arabidopsis


   CEITEC

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  Dr M Samalova, Prof J Hejátko  No more applications being accepted  Competition Funded PhD Project (Students Worldwide)

About the Project

In our lab we are interested in the study of plant hormonal signaling pathways, particularly cytokinins (CKs) in the development of model plant Arabidopsis thaliana (1-4). Our recent preliminary data suggest an important role for CK-regulated genes, namely EXPANSINs, in the control of cell wall (CW) properties. Besides CW critical developmental importance in plants, CW-based biomaterials are exploited in diverse human activities and have high application potential as a source of sustainable and renewable energy for the future. The aim of the project is to investigate a novel role for CKs in the regulation of CW composition and structure during CK-controlled cell differentiation. We hypothesize that CKs control cell differentiation via regulation of biomechanical properties of the CW. As an important part of the project we will employ the CRISPR-Cas9 gene-editing technology and brand-new optical method, Brillouin imaging, developed for the non-invasive measurement of biomechanical CW properties (5). We expect: Highly motivated, ambitious candidates with interest in molecular biology and plants. We offer: Experimental work on own project with the possibility of publication in top-ranked international journals, friendly lab staff, world-class equipment, attractive environment of novel university campus, help with both intellectual and practical problems, competitive salary corresponding to the work efficiency.

Applicants who wish to pursue a degree at the CEITEC PhD programme must hold the equivalent of a Master’s degree (MSc) in similar field (four or five year undergraduate degree). The application can be submitted before obtaining the Master’s degree, however, the applicant should obtain the degree within five month after the application deadline.
Detail information about the admission procedure available at http://ls-phd.ceitec.cz/information-for-applicants/
All general enquiries should be directed to Olga Krizova ([Email Address Removed]). Scientific inquiries can be addressed to the supervisor
+420 5 4949 8476, [Email Address Removed], [Email Address Removed]


Funding Notes

Admission for studies, student registration for the full-time study programme and proper fulfilment of student duties constitute the student’s right to a regular scholarship of 20 000 CZK (730 EUR). Information is available at http://ls-phd.ceitec.cz/information-for-students/#fund
Living costs and other practicalities available at http://ls-phd.ceitec.cz/practical-information-for-life-in-brno/

References

References 1. Dobisova, T., et al. (2017). Plant Physiol 174, 387-404. 2. Paniagua, C., et al. (2017). J Exp Bot. 3. Pernisova, M., et al. (2016). New Phytol 212, 497-509. 4. Zd'arska, M., et al. (2013). Plant Physiology 161, 918-930. 5. Elsayad, K., et al. (2016). Sci Signal 9, rs5.
RG: Jan Hejátko Research Group