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  PhD in stem cell transplantation immunology: mapping the induction of allo-immune effector cells in haematopoietic stem cell transplantation


   Institute of Cellular Medicine

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  Prof M Collins  No more applications being accepted  Funded PhD Project (Students Worldwide)

About the Project

Number of awards:

1

Start date and duration:

September – December 2018 (flexible) for 3 years.

Overview:

More than 1 million patients worldwide are alive today because they received a haematopoietic stem cell transplantation (bone marrow transplant) as therapy for their leukaemia or other blood cancer. The success of this treatment is critically dependent upon the generation of immune responses driven by antigenic differences between the donor and recipient (allo-immunity).

This PhD studentship, offered by the Faculty of Medical Sciences and funded by a bequest from the estate of Alan Bremner Smith, will use state of the art single cell transcriptomic technology to map the induction of allo-immune effector cells following transplantation, with the aim of decoding key transcriptional regulators that augment or inhibit responses and may therefore be exploited in future therapies.

The successful candidate will be interested in immunology or cellular therapy and will join one of the UK’s most research active stem cell transplantation units, supervised by leaders in the fields of myeloid and T cell biology.

For further information please visit: http://www.hudendritic.org/home/people/vacancies-opportunities.

Sponsor:

Alan Bremner Smith - Newcastle University Institute of Cellular Medicine.

Name of supervisor(s):

Professor Matthew Collin (https://bit.ly/2HXnmEq), Dr Arian Laurence (https://bit.ly/2Jy43yK) and Dr Shoba Armanath (https://bit.ly/2r4YXm9), Institute of Cellular Medicine (https://bit.ly/2Fm6qC8).

Eligibility Criteria:

You must have, or expect to achieve, a 2:1 honours degree, or international equivalent, in a subject relating to exercise science, including: Sport and exercise science, biomedicine and nutrition. A further qualification such as an MSc or MRes is advantageous.

The award is available to UK/EU and international applicants. If English is not your first language, you must have IELTS 7, with at least 6.5 in the written component, or equivalent.

How to apply:

You must apply through the University’s online postgraduate application system. To do this please ‘Create a new account’ (https://bit.ly/2I4ckuH).

Only mandatory fields need to be completed. However, you will need to include the following information:
•insert the programme code 8300F in the programme of study section
•select ‘PhD in the Faculty of Medical Sciences – Cellular Medicine’ as the programme of study
•insert the studentship code CL103 in the studentship/partnership reference field
•attach a covering letter and CV. The covering letter must state the title of the studentship, quote the studentship reference code CL103 and state how your interests and experience relate to the project
•attach degree transcripts and certificates and, if English is not your first language, a copy of your English language qualifications.

Funding Notes

100% of UK/EU tuition fees paid and annual living expenses of £14,777. Successful international candidates will be required to make up the difference between the UK/EU and international fee.