Novel implanted bio-sensors to detect real-time recurrence and growth of primary brain tumours

Glioblastoma multiforme (GBM) is the most common and most malignant primary brain tumour. Current management often involves surgery, radiotherapy, and chemotherapy but survival is dismal. The key problem is detecting regrowth of tumour cell near the surgical resection margin, and there is an unmet need to detect and target this recurrence, as a means of prolonging good quality survival. The aim of this project is to develop and test a range of biocompatible sensors – amenable to neurosurgical implantation – that can detect tumour regrowth in near-real time and with high spatial resolution.

This is a four-year PhD that will be undertaken within the Centre for Doctoral Training in Intelligent Sensing and Measurement. See http://www.cdt-ism.org for programme details and information on how to apply.