Stereoselective Hydro and Carbosilylation Reactions and Applications in Synthesis

You will build on recent work in the Cook group developing new transition metal catalysed enantioselective reactions for the synthesis of organosilicon compounds. These versatile compounds have many applications as intermediates in synthesis but also medicinal and materials applications. A series of reactions will be developed including enantioselective hydrosilylation and carbosilyations to rapidly build complex stereodefined products. We will then use these intermediates in the arena of complex molecule synthesis. This will build skills in enantioselective syntheis, transition metal catalysis, organometallic chemistry and target molecule synthesis.

Experience in synthetic organic chemistry is required and additional experience in transition metal catalysis would be advantageous. Please contact Dr Matthew Cook for further details and send a detailed CV to [Email Address Removed] in the first instance.

The Cook group is a productive and well funded group which currently consists of 3 PhD students, one postdoctoral fellow and several undergraduate researchers which operate in very well equipped laboratories. For further details see: https://sites.google.com/site/cookchemistrygroup/home