MRes/PhD Studentship in Cell and Molecular Biosciences - Investigating the Structure and Function of the Bacterial Cell Division Machinery with Super-resolution Microscopy


   Faculty of Medical Sciences Graduate School

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Dr S Holden  Applications accepted all year round

About the Project

Interested in combining bacterial cell biology with cutting-edge super-resolution microscopy techniques to figure out how bacteria divide? This project will investigate the spatial organization of the bacterial cytoskeleton, in order to improve our understanding of bacterial cell division. Ultimately this should help inform the development of next-generation antibiotics targeting bacterial cell division.

The structure and dynamics of the bacterial cell division machinery remain mysterious because this machinery is spatially organized on the nanometre scale, below the resolution of conventional light microscopy. The studentship will focus on using single molecule super-resolution microscopy, in combination with microbiology and molecular biology approaches, to study bacterial cell division in living cells (primarily Bacillus subtilis), in order to elucidate the physical mechanisms of cytokinesis.

Cross-disciplinary training will be provided in advanced microscopy, biophysics, molecular biology and microbiology.

Funding Notes

Sponsor: Faculty of Medical Sciences, Newcastle University

The award covers tuition fees at the UK/EU rate and an annual stipend of £14,057 (for 2015/16). The studentship is one year MRes followed by 3 years PhD. A 3 year PhD may be considered if you already have a Master’s degree in a relevant subject.

Project Start Date: 28th September 2015 (MRes), September- December 2015 (PhD).

References

You must have, or expect to achieve, a minimum of an upper-second-class Honours degree or international equivalent, in a relevant subject (eg. biological sciences, microbiology, biochemistry, physical sciences or engineering). If you wish to apply for a 3 year PhD programme you must have or expect to achieve a further qualification such as, for example, an MRes.

The award is available to UK/EU applicants only.

You must apply through the University’s online postgraduate application form - http://www.ncl.ac.uk/postgraduate/apply/. Only mandatory fields need to be completed but applicants must:
• insert the programme code 4850F in the programme of study section
• select ‘Master of Research/Doctor of Philosophy (Medical Sciences) - as the programme of study
• insert the studentship code CB119 in the studentship/partnership reference field
• attach a covering letter and CV. The covering letter must state the title of the studentship, quote the studentship reference code CB119 and state how your interests and experience relate to the project
• attach degree transcripts and certificates and, if English is not your first language, a copy of your English language qualifications