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Dr S Becker
Applications accepted all year round
Competition Funded PhD Project (Students Worldwide)
About the Project
This research focus lies in applied Transport Phenomena and the Thermodynamics associated with the physiological behavior of living tissues.
Specifically: Modelling the physics associated with electroporation of the skin.
While the overall research involves the application of fundamental physics and mathematics to the understanding of physical phenomena associated with biological processes, the current research focuses on:
One of the biggest challenges of recent advances in pharmacy and biotechnology of the transdermal delivery of drugs is finding the most effective methods of delivering these molecules to targeted sites inside the human body. Modification of skin permeability to increase transdermal delivery has been achieved by passive and active methods of enhancement. While passive methods base on the formulation and chemical approaches, active use physical force to breach the skin barrier and/or provide driving force on the drug. Electroporation is a well established method used to transiently create aqueous pores in phospholipid bilayers of cell membrane, using electric pulses of high voltage and short duration. This project develops models of the associated physical phenomena.
==> this project area thus involves a mixture of modeling, computation, clinical testing and/or data, and mathematics, as well as seeking to enhance models and develop new ideas
Specifically: Modelling the physics associated with electroporation of the skin.
While the overall research involves the application of fundamental physics and mathematics to the understanding of physical phenomena associated with biological processes, the current research focuses on:
One of the biggest challenges of recent advances in pharmacy and biotechnology of the transdermal delivery of drugs is finding the most effective methods of delivering these molecules to targeted sites inside the human body. Modification of skin permeability to increase transdermal delivery has been achieved by passive and active methods of enhancement. While passive methods base on the formulation and chemical approaches, active use physical force to breach the skin barrier and/or provide driving force on the drug. Electroporation is a well established method used to transiently create aqueous pores in phospholipid bilayers of cell membrane, using electric pulses of high voltage and short duration. This project develops models of the associated physical phenomena.
==> this project area thus involves a mixture of modeling, computation, clinical testing and/or data, and mathematics, as well as seeking to enhance models and develop new ideas
Funding Notes
Regarding funding opportunities, we have several scholarships we are happy to help you try and obtain. Specifically:
• The NZIDRS Scholarship: http://www.newzealandeducated.com/scholarships/page1.html
• Our Dept Premier Scholarship: http://www.mech.canterbury.ac.nz/pgprojects/scholarships.shtml
• NZAID: http://www.nzaid.govt.nz/scholarships/nzds.html -- if applicable
• UC doctoral scholarships regular and international (see links): http://www.mech.canterbury.ac.nz/scholarship/pg_schols.shtml
We also have regular funding for some of this research at any given time, but not always available or unrestricted for student support. Please contact us directly for more information!
• The NZIDRS Scholarship: http://www.newzealandeducated.com/scholarships/page1.html
• Our Dept Premier Scholarship: http://www.mech.canterbury.ac.nz/pgprojects/scholarships.shtml
• NZAID: http://www.nzaid.govt.nz/scholarships/nzds.html -- if applicable
• UC doctoral scholarships regular and international (see links): http://www.mech.canterbury.ac.nz/scholarship/pg_schols.shtml
We also have regular funding for some of this research at any given time, but not always available or unrestricted for student support. Please contact us directly for more information!
References
For a full bibliography of our work in this and other areas please see the Publications link at:
http://www.mech.canterbury.ac.nz/people/becker.shtml
http://www.mech.canterbury.ac.nz/people/becker.shtml
