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Dr Thomas Prellberg
No more applications being accepted
Competition Funded PhD Project (UK Students Only)
About the Project
Project area: Applied Mathematics
Start date: September 2012
Generic properties of physical polymers can be modelled by self-avoiding walks on a regular lattice. In order to model DNA, one adds stiffness and gives the lattice polymer a ribbon-like structure. Additionally, a pulling force or torque is added to one or more segments of the polymer.
This ties in with very recent developments of experimental techniques that have enabled sophisticated and sensitive experiments on supercoiling in DNA by applying torsion to the end of a DNA strand via optical tweezers.
Using a uniform sampling algorithm, a simple lattice ribbon model will be adapted to model this scenario. Within the lattice model one can successively simulate ever more complex situations, carefully studying the interplay of generic parameters such as stiffness and intrinsic twist of the DNA, and its response to external forcing and twisting.
The successful candidate should have a first degree in Mathematics or Physics. Knowledge of Statistical Physics and experience with programming in C or C++ is highly desirable.
The School of Mathematical Sciences is one of the largest UK mathematical science departments and is one of five Schools in the Faculty of Science and Engineering at Queen Mary. The School offers energetic and diverse postgraduate activity across the spectrum of mathematical sciences from pure and applied mathematics to statistics. Our staff includes international leaders in many areas of mathematical research, and the School is a hive of activity, providing a vibrant postgraduate life. For more information about the School please see http://www.maths.qmul.ac.uk/
Informal enquiries can be made by email to Dr Thomas Prellberg, [Email Address Removed]
To apply for this studentship and for entry on to the mathematics research programme please fill in online application form at http://www.qmul.ac.uk/postgraduate/applyresearchdegrees/index.html
If you have any queries regarding the application process please contact the postgraduate administrative officer ([Email Address Removed] / +44 (0)20 7882 5454).
Start date: September 2012
Generic properties of physical polymers can be modelled by self-avoiding walks on a regular lattice. In order to model DNA, one adds stiffness and gives the lattice polymer a ribbon-like structure. Additionally, a pulling force or torque is added to one or more segments of the polymer.
This ties in with very recent developments of experimental techniques that have enabled sophisticated and sensitive experiments on supercoiling in DNA by applying torsion to the end of a DNA strand via optical tweezers.
Using a uniform sampling algorithm, a simple lattice ribbon model will be adapted to model this scenario. Within the lattice model one can successively simulate ever more complex situations, carefully studying the interplay of generic parameters such as stiffness and intrinsic twist of the DNA, and its response to external forcing and twisting.
The successful candidate should have a first degree in Mathematics or Physics. Knowledge of Statistical Physics and experience with programming in C or C++ is highly desirable.
The School of Mathematical Sciences is one of the largest UK mathematical science departments and is one of five Schools in the Faculty of Science and Engineering at Queen Mary. The School offers energetic and diverse postgraduate activity across the spectrum of mathematical sciences from pure and applied mathematics to statistics. Our staff includes international leaders in many areas of mathematical research, and the School is a hive of activity, providing a vibrant postgraduate life. For more information about the School please see http://www.maths.qmul.ac.uk/
Informal enquiries can be made by email to Dr Thomas Prellberg, [Email Address Removed]
To apply for this studentship and for entry on to the mathematics research programme please fill in online application form at http://www.qmul.ac.uk/postgraduate/applyresearchdegrees/index.html
If you have any queries regarding the application process please contact the postgraduate administrative officer ([Email Address Removed] / +44 (0)20 7882 5454).
Funding Notes
The studentship is funded by EPSRC and will cover student fees and a tax-free stipend starting at £15,590 per annum. Please see the following webpage for eligibility criteria
http://www.epsrc.ac.uk/funding/students/Pages/eligibility.aspx
http://www.epsrc.ac.uk/funding/students/Pages/eligibility.aspx
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