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Prof M Bradley
Prof Colin Campbell
No more applications being accepted
Funded PhD Project (Students Worldwide)
About the Project
This project is one of ten (10), four-year PhD Studentships funded by Medical Research Scotland (http://www.medicalresearchscotland.org.uk/funding.htm) and delivered jointly by the named University and Company. The Studentship will provide the first-class academic and commercial training needed to equip the successful student for a science career in an increasingly competitive market.
Polymer microarrays for the rapid identification of substrates for the enrichment of rare cell types, mitochondrial DNA capture and peptide deformylation and scale-up for practical application – delivered by the University of Edinburgh and Altrika Technologies Ltd (http://www.altrika.com).
Academic supervisor: Professor Mark Bradley; Company supervisor: Dr Guilheim Tourniaire
The project will involve the development of the Bradley group’s unique inkjet printing polymer microarray platform (see references below) and its application in a number of medically relevant areas. Work will be in collaboration with Altrika Technologies and with a number of clinical groups in Edinburgh (Royal Infirmary of Edinburgh). Specifically we will take this technology into new directions with the generation of arrays of up to 5000 polymers to allow the discovery of new polymers for specific bio-molecule capture and cell enrichment of medical importance.
The candidate should have a chemical background, but a keen desire to work in the biomedical arena and be prepared to collaborate extensively with clinical research groups. To apply please send a detailed CV and contact details of 2 referees to Amanda Ewing(PA to Professor Bradley)
Polymer microarrays for the rapid identification of substrates for the enrichment of rare cell types, mitochondrial DNA capture and peptide deformylation and scale-up for practical application – delivered by the University of Edinburgh and Altrika Technologies Ltd (http://www.altrika.com).
Academic supervisor: Professor Mark Bradley; Company supervisor: Dr Guilheim Tourniaire
The project will involve the development of the Bradley group’s unique inkjet printing polymer microarray platform (see references below) and its application in a number of medically relevant areas. Work will be in collaboration with Altrika Technologies and with a number of clinical groups in Edinburgh (Royal Infirmary of Edinburgh). Specifically we will take this technology into new directions with the generation of arrays of up to 5000 polymers to allow the discovery of new polymers for specific bio-molecule capture and cell enrichment of medical importance.
The candidate should have a chemical background, but a keen desire to work in the biomedical arena and be prepared to collaborate extensively with clinical research groups. To apply please send a detailed CV and contact details of 2 referees to Amanda Ewing(PA to Professor Bradley)
Funding Notes
The PhD Studentship provides: an annual tax-free stipend of £16,000, increasing to £16,500 over the four years; tuition fees at UK/EU rates only; and consumables. Please note international fees are not covered.
References
(i). A microarray approach to the identification of polyurethanes for the isolation of human skeletal progenitor cells and augmentation of skeletal cell growth, Biomaterials, 2009, 30, 1045
(ii). A cooperative polymer-DNA microarray approach to biomaterial investigation, Lab Chip 2009, 9, 397.
(iii). Strategies for cell manipulation and skeletal tissue engineering using high-throughput polymer blend formulation and microarray techniques, Biomaterials 2010, 2216.
(iv). Versatile biocompatible polymer hydrogels: scaffolds for cell growth, Angew Chemie, 2009, 48, 978.
(v). Colonising new frontiers - microarrays reveal biofilm modulating polymers, J Mater Chem, 2011, 21, 96.
(vi). Polymers for the rapid and effective activation and aggregation of platelets, Biomaterials, 2011, 32, 7034-7041.
(ii). A cooperative polymer-DNA microarray approach to biomaterial investigation, Lab Chip 2009, 9, 397.
(iii). Strategies for cell manipulation and skeletal tissue engineering using high-throughput polymer blend formulation and microarray techniques, Biomaterials 2010, 2216.
(iv). Versatile biocompatible polymer hydrogels: scaffolds for cell growth, Angew Chemie, 2009, 48, 978.
(v). Colonising new frontiers - microarrays reveal biofilm modulating polymers, J Mater Chem, 2011, 21, 96.
(vi). Polymers for the rapid and effective activation and aggregation of platelets, Biomaterials, 2011, 32, 7034-7041.
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View other supervisors at University of EdinburghCareer overview
Professor Colin Campbell is the Head of the Organic Chemistry Section and co-Head of the IRR Chemistry Hub at the University of Edinburgh. He has previously served as the Director of the EPSRC and MRC Centre for Doctoral Training in Optical Medical Imaging (OPTIMA). Professor Campbell was a Fulbright Awardee during the 2018-2019 academic year and held the position of Sabbatical Professor at the Biofrontiers Institute, University of Colorado, Boulder, during the same period. His research focuses on nanosensors, electrochemistry, Surface Enhanced Raman Spectroscopy (SERS), nanotechnology, and redox biology. Professor Campbell's group has pioneered the use of SERS to make measurements in 3D tissue models and has developed new sensors for measuring pH, redox potential, enzyme activity, and the concentration of small molecules. The collaborative nature of his work has facilitated access to patient materials, enabling advancements in the application of SERS in biology and medicine.
Research interests
Professor Colin Campbell's research focuses on nanosensors, electrochemistry, Surface Enhanced Raman Spectroscopy (SERS), nanotechnology, and redox biology. They have pioneered the use of SERS to make measurements in 3D tissue models, developing new sensors to measure pH, redox potential, enzyme activity, and the concentration of small molecules. Their work involves creating new materials for SERS that enable research in complex biological microenvironments. Professor Campbell's collaborative approach has provided access to patient materials, advancing the application of SERS in biology and medicine. Current research interests include developing new sensors, incorporating sensors into 3D tissue models, and making measurements in tissue and biofluids. Additionally, they engage in knowledge exchange by turning scientific data and ideas into music as a means of communicating scientific concepts.
