This project is no longer listed on FindAPhD.com and may not be available.
Click here to search FindAPhD.com for PhD studentship opportunities
Prof E Davies, Dr S Mackenzie
No more applications being accepted
About the Project
Deadline: Rolling selection process. First round application closing date: May 6 2013. Second round closing date: July 1 2013
Stipend: £13,726 per annum
Start date: October 2013
This MRC funded project provides students with cutting-edge research opportunities in Medical Research. Projects will align with MRC strategic priorities, www.mrc.ac.uk
The steroid hormone aldosterone is produced by the adrenal gland and plays an important role in sodium homeostasis and blood pressure control and its circulating level is an important determinant of cardiovascular risk and outcome. Approximately 10-15 % of patients with hypertension have excess aldosterone production (Primary hyperaldosteronism). Understanding its production and regulation is central to understanding its role in these common conditions and to the development of new cardiovascular treatments.
Recent studies have shown that microRNA molecules have a significant impact on mammalian regulatory mechanisms, and our preliminary studies show this is also true of aldosterone production. This project will combine our extensive experience of aldosterone research with cutting edge molecular biology and bioinformatic methods to examine microRNA profiles in the circulation and in the adrenal glands in patients with hypertension due to excess aldosterone production. By investigating and analysing these microRNAs patterns, this project has the potential to discover novel biomarkers for the diagnosis of primary aldosteronism, while also shedding light on the molecular events that initiate tumour formation and excess aldosterone overproduction.
Visit our website for more information: http://www.gla.ac.uk/colleges/mvls/graduateschool/researchopportunities/scholarshipopportunities/medicalresearchcouncil/#tabs=0
Applicant Instructions
These are 3.5-year PhD studentships and students should apply online here: http://www.gla.ac.uk/research/opportunities/howtoapplyforaresearchdegree/
Applicants will normally be expected to reside (or have residency) within the UK. EU nationals will have to demonstrate that they have spent the three years prior to application resident in the UK (this can include residence whilst undertaking undergraduate study). Applicants should have obtained, or expect to obtain a 2:1 or 1st class Honours degree in a relevant subject. The financial package will include a 3.5 year stipend, approved University fees, Research Training Support Grant and a conference allowance.
On the Programme of Study section of the application please select “MVLS PhD” from the drop down menu. On this same page please place the project title(s) within the free text area and note the project supervisor(s).
Please ensure that all supporting documents are uploaded at point of application, for example:
- Copy of Academic and Professional qualifications
- CV (including letter of application/personal statement)
- 2 x references
Further supporting documents are requested on the online applications system, and should be uploaded where relevant. General enquiries regarding the programme and application procedure should be directed to Alexis Merry: [Email Address Removed]
Stipend: £13,726 per annum
Start date: October 2013
This MRC funded project provides students with cutting-edge research opportunities in Medical Research. Projects will align with MRC strategic priorities, www.mrc.ac.uk
The steroid hormone aldosterone is produced by the adrenal gland and plays an important role in sodium homeostasis and blood pressure control and its circulating level is an important determinant of cardiovascular risk and outcome. Approximately 10-15 % of patients with hypertension have excess aldosterone production (Primary hyperaldosteronism). Understanding its production and regulation is central to understanding its role in these common conditions and to the development of new cardiovascular treatments.
Recent studies have shown that microRNA molecules have a significant impact on mammalian regulatory mechanisms, and our preliminary studies show this is also true of aldosterone production. This project will combine our extensive experience of aldosterone research with cutting edge molecular biology and bioinformatic methods to examine microRNA profiles in the circulation and in the adrenal glands in patients with hypertension due to excess aldosterone production. By investigating and analysing these microRNAs patterns, this project has the potential to discover novel biomarkers for the diagnosis of primary aldosteronism, while also shedding light on the molecular events that initiate tumour formation and excess aldosterone overproduction.
Visit our website for more information: http://www.gla.ac.uk/colleges/mvls/graduateschool/researchopportunities/scholarshipopportunities/medicalresearchcouncil/#tabs=0
Applicant Instructions
These are 3.5-year PhD studentships and students should apply online here: http://www.gla.ac.uk/research/opportunities/howtoapplyforaresearchdegree/
Applicants will normally be expected to reside (or have residency) within the UK. EU nationals will have to demonstrate that they have spent the three years prior to application resident in the UK (this can include residence whilst undertaking undergraduate study). Applicants should have obtained, or expect to obtain a 2:1 or 1st class Honours degree in a relevant subject. The financial package will include a 3.5 year stipend, approved University fees, Research Training Support Grant and a conference allowance.
On the Programme of Study section of the application please select “MVLS PhD” from the drop down menu. On this same page please place the project title(s) within the free text area and note the project supervisor(s).
Please ensure that all supporting documents are uploaded at point of application, for example:
- Copy of Academic and Professional qualifications
- CV (including letter of application/personal statement)
- 2 x references
Further supporting documents are requested on the online applications system, and should be uploaded where relevant. General enquiries regarding the programme and application procedure should be directed to Alexis Merry: [Email Address Removed]
Where will I study?
Continue with Facebook