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  Faster Synthesis of Natural Products through Transition-Metal-Catalysed C-H and C-C bonds Activation


   Department of Chemistry

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Dr C Aissa  Applications accepted all year round  Funded PhD Project (European/UK Students Only)

About the Project

The development of environmentally benign chemical reactions is a critical challenge facing society, which constantly demands new drugs and new materials to improve the quality of life without increasing the pressure on natural resources. Carbon-carbon (C–C) bond formation through transition-metal-catalysed activation of otherwise inert bonds constitutes a very promising strategy to develop sustainable synthetic chemistry and address those issues.
We are looking for a motivated and talented individual to work on our current endeavour towards the development of transition-metal-catalysed C-H and C-C bonds activation and their application to the total synthesis of natural products of biological relevance. Examples of our recent work can be found in the reference section. The ideal candidate will have a Master degree in Chemistry with good knowledge of organic chemistry and catalysis.
Our research programme is perfectly suited for the training of postgraduate student, who desire to acquire an in-depth knowledge of cutting-edge transition metal catalysis and organic chemistry. Hence, individuals who collaborate to this programme will be prepared to their future career in an optimal manner.
Our research group is located in the recently refurbished Synthetic Organic Chemistry Laboratory of the University of Liverpool (£4.5 M), which offers an ideal environment to learn new techniques and do outstanding science. Each co-worker benefits from a fume cupboard, several stirring plates, a high-vacuum pump, a rotary evaporator etc ... as well as a privileged access to a 500 MHz NMR apparatus, GC, HPLC, and glovebox.

Funding Notes

Start date: October 2012. Funding is secured for 3.5 years through a teaching assistant contract (up to 6h/week). it covers both tuition fees and a maintenance grant (equivalent to current level of EPSRC DTA). Non-native speakers must hold a certificate of language proficiency before the starting date (see details of language requirements at http://www.liv.ac.uk/study/international/countries/english-language.htm#pg).

References

Angew. Chem. Int. Ed. 2010, Vol 49, p 620
Chem. Commun. 2011, Vol 47, p 10957
Chem. Eur. J. 2012, Vol 18, p 3486

Where will I study?


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