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Dr D Thomas
No more applications being accepted
Funded PhD Project (European/UK Students Only)
About the Project
3-year PhD Studentship in Magnetic Resonance Imaging funded by Kidney Research UK
Imaging and Biophysics Unit, UCL Institute of Child Health
Studentship Description:
Arterial spin labelling (ASL) is a non-invasive magnetic resonance imaging (MRI) method for measuring blood flow in the body. In particular, it is able to measure the rate of delivery of blood to the body’s organs, and therefore provides a direct quantitative assessment of the supply of nutritive flow to the tissue. This provides complementary physiological information to the anatomical images obtained using conventional MRI, and enables a more complete evaluation of patients with disturbed haemodynamics.
Our group are actively engaged in developing ASL as a method to measure kidney perfusion in adult and paediatric patients with impaired renal function, as well as in healthy kidney donors pre- and post-donation. Members of the group are also involved in developing ASL for brain perfusion and collaborating with senior members at the Institute of Neurology.
The focus of this PhD studentship will be to develop and implement optimal acquisition methods and post-processing strategies to enable accurate and reliable quantification of renal perfusion using ASL. In particular, this will include improving the robustness of the technique to patient motion and evaluating the biophysical models used to convert the MRI signal to quantitative blood flow units. The project will involve computer simulation of MRI pulse sequences, pulse sequence programming and data acquisition on a clinical Siemens 1.5T Avanto MRI scanner, and implementation and testing of advanced image reconstruction and registration methods (in collaboration with our colleagues at the UCL Centre for Medical Image Computing). We expect that the variety of activities involved in this project will allow the student to gain broad MRI experience and develop a range of transferable skills.
- Project Description, see http://www.ucl.ac.uk/ich/education-ich/phd-prog/phd_studentships/kruk-isky-gordon-project-desc
Person Specification:
We are looking for an enthusiastic and well-motivated student to work with us in this exciting area of research. Applicants should have, or expect to receive, a first class or an upper second class honours degree in physics, engineering or a related area, and to have a keen interest in cross-disciplinary research bridging the gap between the physical and biomedical sciences. Previous experience in MRI and/or computer programming (e.g. C++, Matlab, etc.) is desirable but not essential.
Eligibility:
The student will receive a starting stipend of £15,740 per annum as well as the cost of tuition fees for UK/EU students (applicants from non-EU countries can apply but will have to personally fund the difference between the home/EU rate and the overseas rate.
The project will start September/October 2013.
Applications (including a covering letter, CV and the names of two referees) should be sent to Dr David Thomas at [Email Address Removed]. If you would like further information about the studentship, please contact Dr Thomas by email.
The closing date for applications is 31st May 2013.
Imaging and Biophysics Unit, UCL Institute of Child Health
Studentship Description:
Arterial spin labelling (ASL) is a non-invasive magnetic resonance imaging (MRI) method for measuring blood flow in the body. In particular, it is able to measure the rate of delivery of blood to the body’s organs, and therefore provides a direct quantitative assessment of the supply of nutritive flow to the tissue. This provides complementary physiological information to the anatomical images obtained using conventional MRI, and enables a more complete evaluation of patients with disturbed haemodynamics.
Our group are actively engaged in developing ASL as a method to measure kidney perfusion in adult and paediatric patients with impaired renal function, as well as in healthy kidney donors pre- and post-donation. Members of the group are also involved in developing ASL for brain perfusion and collaborating with senior members at the Institute of Neurology.
The focus of this PhD studentship will be to develop and implement optimal acquisition methods and post-processing strategies to enable accurate and reliable quantification of renal perfusion using ASL. In particular, this will include improving the robustness of the technique to patient motion and evaluating the biophysical models used to convert the MRI signal to quantitative blood flow units. The project will involve computer simulation of MRI pulse sequences, pulse sequence programming and data acquisition on a clinical Siemens 1.5T Avanto MRI scanner, and implementation and testing of advanced image reconstruction and registration methods (in collaboration with our colleagues at the UCL Centre for Medical Image Computing). We expect that the variety of activities involved in this project will allow the student to gain broad MRI experience and develop a range of transferable skills.
- Project Description, see http://www.ucl.ac.uk/ich/education-ich/phd-prog/phd_studentships/kruk-isky-gordon-project-desc
Person Specification:
We are looking for an enthusiastic and well-motivated student to work with us in this exciting area of research. Applicants should have, or expect to receive, a first class or an upper second class honours degree in physics, engineering or a related area, and to have a keen interest in cross-disciplinary research bridging the gap between the physical and biomedical sciences. Previous experience in MRI and/or computer programming (e.g. C++, Matlab, etc.) is desirable but not essential.
Eligibility:
The student will receive a starting stipend of £15,740 per annum as well as the cost of tuition fees for UK/EU students (applicants from non-EU countries can apply but will have to personally fund the difference between the home/EU rate and the overseas rate.
The project will start September/October 2013.
Applications (including a covering letter, CV and the names of two referees) should be sent to Dr David Thomas at [Email Address Removed]. If you would like further information about the studentship, please contact Dr Thomas by email.
The closing date for applications is 31st May 2013.
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