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  PhD studentship - Regulation of DNA replication by the central carbon metabolism (based within the Centre for Biomolecular Sciences)


   School of Chemistry

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Prof P Soultanas  Applications accepted all year round

About the Project

Fully funded PhD studentship (October 2012); (CBS) (http://www.nottingham.ac.uk/cbs/index.aspx), School of Chemistry, University of Nottingham, UK.

The above studentship is available in Prof. Panos Soultanas’ group (http://www.nottingham.ac.uk/chemistry/people/panos.soultanas) to work on the molecular mechanisms that underpin regulation of DNA replication by the central carbon metabolism. Applicants should have (or be expected to obtain) a first or upper second class BSc honours degree in a Life Sciences subject. The position is available only to UK and/or EU nationals.

Our preliminary work has uncovered that the metabolism-replication link depends on metabolic signals originating from the central carbon metabolism core and is sensed by the replication initiation protein DnaA and the replicative helicase, the primase and the lagging strand polymerase in Bacillus subtilis. The subject of this research is to uncover the molecular details of this regulatory link. Further details can be obtained directly by contacting Prof. Panos Soultanas either by e-mail ([Email Address Removed]) or by phone (44(0)115-9513525).

The CBS houses over 300 scientists from 5 different Schools and Departments across 3 Faculties, in a state of the art research building with a strong interdisciplinary ethos. A total of £40 million has been invested to create an excellent blend of biology, chemistry and engineering laboratories.

To apply, please access: http://pgstudy.nottingham.ac.uk/apply-postgraduate-course/apply-online.aspx stating that you want to join Prof. Soultanas’ group (CBS, School of Chemistry). The application number verifying that your application has been uploaded online together with a full CV should be forwarded directly to Prof. Soultanas (email: [Email Address Removed]). Applications will be considered on an ongoing basis until the position is filled by the appropriate student. Please quote ref. SCI/1087. This studentship will remain open until filled.

Where will I study?

 About the Project